Protein Alignment SecCl and gabra4

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001017822.1
• Gene: gabra4 / 550520
• ZFINID: ZDB-GENE-050417-360
• Length: 557
• Species: Danio rerio
• Alignment Length: 528
• Identity: 128/528 - (24%)
• Similarity: 220/528 - (41%)
• Gaps: 93/528 - (17%)

  Fly    45 TQLIQRLTHVCRYDRLERPFEYDSDGKRLPIV-VKTRIYVYFLQNLNSDLLQFKMHALLQLRFQD 108
            |:::.||  :..||...||      |...|:. |||.|||.....::...:::.|....:..:.|
Zfish    49 TRILDRL--LDGYDNRLRP------GFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWVD 105

  Fly   109 KRLAYKA---FNRSDNILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTR 170
            :||.|:.   ..|.:|::..|     :|.|..||.|.:.|........:.|..:...|.::.:.|
Zfish   106 RRLRYEGPVEILRLNNLMVTK-----VWTPDTFFRNGKRSVAHNMTAPNRLFRIMKNGTILYTMR 165

  Fly   171 MQASLYCWMNFQKFPFDQQFCSTVLESWMYNTSDLILEWE--PHTPISFDPE-MRLTEYNMAQFW 232
            :..|..|.|....||.|...|.....|:.|..:::|..|.  |...:...|| ..|.:|::....
Zfish   166 LTISAECPMRLVNFPMDGHSCPLKFGSYAYPKTEMIYTWTKGPQHSVEVPPESSSLVQYDLIGQT 230

  Fly   233 HNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASP 297
            .::..|:|         ..|.|..::...:|||::|::::..|:|.:|.|.:|.||||:..::.|
Zfish   231 VSSETVKS---------ITGEYVVMTVYFHLKRKMGYFMIQTYIPCIMTVILSQVSFWINKESVP 286

  Fly   298 PRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEVWFLG-CTFFIFGSLVEFAFVN--------- 352
            .|.:.|.:|:|:..|||.|...:||||||....: ||:. |..|:|.:|:|||.||
Zfish   287 ARTVFGITTVLTMTTLSISARHSLPKVSYATAMD-WFIAVCFAFVFSALIEFAAVNYFTNAQAER 350

  Fly   353 ----------------TIWRRKENIELKKVNS------KYIIKSTLTPRPARRQIGGSLSNESRA 395
                            :..:.|:..|:.:.||      :..:.|.:.|:...::...:.:: |::
Zfish   351 AKRKQAKAAAAASVKSSTGKNKDTEEVLQQNSDTNGNLRKRVNSNIQPQAESKKTQRTEAS-SKS 414

  Fly   396 RSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICSARTNNDHIVDV 460
            .:.||...:.|.:.|...|..:    |::...:.|:........|.:.:.|..:...........
Zfish   415 GASSSKPTLTSQSSSTSEGTSS----FSSQSRLSPSSASQSNAAASSSSASKTTPPAPPSTPTVP 475

  Fly   461 DKDKKDTPPTFTT-------------------MTPQEI------AMWIDRRSRFLFPAMFLAFNA 500
            ||....|.|..:.                   ..||..      |..||..:|.|||..|.|||.
Zfish   476 DKPSPGTTPAGSAPLHHLLGPKLENIKKKEAKAQPQPAAPATGGASKIDEYARILFPVSFGAFNM 540

  Fly   501 LYWTFVYV 508
            :||. ||:
Zfish   541 VYWV-VYL 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	126/523 (24%)
		Neur_chan_LBD	44..267	CDD:280998	55/228 (24%)
		Neur_chan_memb	275..503	CDD:280999	68/284 (24%)
gabra4	NP_001017822.1	Neur_chan_LBD	49..256	CDD:280998	55/228 (24%)
		Neur_chan_memb	263..543	CDD:280999	68/285 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900