Protein Alignment SecCl and ort

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 125/551 - (22%)
• Similarity: 222/551 - (40%)
• Gaps: 122/551 - (22%)

  Fly     9 IFWITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRL--THVCRYDRLERPFEYDSDGK 71
            :|.|.::::.:|            |......|..||:..|..:  ..:.|||::..|   ..:|:
  Fly     2 VFQIIILVICTI------------CMKHYAKGEFQQSLAITDILPEDIKRYDKMRPP---KKEGQ 51

  Fly    72 RLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSE-----R 131
              |.:|...:.|..|.:::.:.:.:.........::|.||     ...:|:..:..|.|     .
  Fly    52 --PTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRL-----RLPENMTQEYRLLEVDWLKN 109

  Fly   132 LWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLE 196
            :|.|..||.|.:..:.......:....|..:..::...::...|.|.|||..:|.|.|.|...:|
  Fly   110 MWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAIYPHDTQECKLQME 174

  Fly   197 SWMYNTSDLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTV 261
            |..:.|.|||.:|:|.||:..|..:.|.:         ..:::::..:.......||::.|....
  Fly   175 SLSHTTDDLIFQWDPTTPLVVDENIELPQ---------VALIRNETADCTQVYSTGNFTCLEVVF 230

  Fly   262 NLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSY 326
            .|||.:.:|:.:.|:|:.|||.:||||||::.:|:|.|:.||.:::|:..|..:....:||.|||
  Fly   231 TLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSY 295

  Fly   327 IKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPAR---RQIGGS 388
            :|..:.:...||.|:|.:|:|:..:|                 .::..|..|:|..   :.:.|.
  Fly   296 LKAVDAFMSVCTVFVFMALMEYCLIN-----------------IVLSDTPIPKPMAYPPKPVAGD 343

  Fly   389 LSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVH--PNLPIIRTECAEADTVSICSAR 451
                                ...:.|.|....|.|:..:..  ..||:...:..:.:  .|....
  Fly   344 --------------------GPKKEGEGAPPGGSNSTASKQQATMLPLADEKIEKIE--KIFDEM 386

  Fly   452 TNNDHIV---------DVDKDKKDTP---------PTFT------------------TMTPQE-- 478
            |.|..||         .:|.|....|         ||..                  .:||.:
  Fly   387 TKNRRIVTTTRRVVRPPLDADGPWIPRQESRIILTPTIAPPPPPPQPAAPEPELPKPKLTPAQER 451

  Fly   479 --IAMWIDRRSRFLFPAMFLAFNALYWTFVY 507
              .|::|||.||.||||:|.:.|.:||...|
  Fly   452 LKRAIYIDRSSRVLFPALFASLNGIYWCVFY 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	119/513 (23%)
		Neur_chan_LBD	44..267	CDD:280998	50/229 (22%)
		Neur_chan_memb	275..503	CDD:280999	65/272 (24%)
ort	NP_524406.1	LIC	31..481	CDD:273305	116/507 (23%)
		Neur_chan_LBD	38..235	CDD:280998	47/215 (22%)
		Neur_chan_memb	243..>334	CDD:280999	34/107 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910