Protein Alignment SecCl and GluClalpha

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_061519540.1
• Gene: GluClalpha / 4577187
• VectorBaseID: AGAMI1_003458
• Length: 468
• Species: Anopheles gambiae
• Alignment Length: 531
• Identity: 142/531 - (26%)
• Similarity: 235/531 - (44%)
• Gaps: 110/531 - (20%)

  Fly     9 IFWITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYD-SDGKR 72
            ||:...:...|:..:..|...|:|            .:::.::....:||...||...: :|.|
Mosquito    10 IFYFACLCSASLANNAKVNFREKE------------KKILDQILGAGKYDARIRPSGINGTDDK- 61

  Fly    73 LPIVVKTRIYV-YFLQNLNSDLLQFKMHALLQLRFQ----DKRLAYKAFNRSDNILGQ-KHL--- 128
                 .|:::| .||::: |.:..:||...:||.|:    |:||.:      |:|.|: |:|
Mosquito    62 -----ATQVFVNMFLRSI-SKIDDYKMEYSVQLTFREQWLDERLKF------DDIGGRLKYLTLT 114

  Fly   129 -SERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCS 192
             :.|:|:|.:||:||:|.........:|...:.|.|:|:.|.|:..:|.|.||.:.:|.|:|.||
Mosquito   115 EANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPYGSVLYSIRISLTLACPMNLKLYPLDRQVCS 179

  Fly   193 TVLESWMYNTSDLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSL 257
            ..:.|:.:.|:||:..|:...|:.....:.|..:.:.:|       .:|..|.:..  .|.||.|
Mosquito   180 LRMASYGWTTADLVFLWKEGDPVQVVKNLHLPRFTLEKF-------LTDYCNSKTN--TGEYSCL 235

  Fly   258 SFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLP 322
            ...:..|||..:||:..|:|..|:|.:|||||||...|.|.|:.||.:|:|:..|.:|..:.:||
Mosquito   236 KVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLP 300

  Fly   323 KVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWR--------RKENIELKKVNSKYI-------- 371
            .|||.|..:||...|..|:||:|:|||.||...|        .:||::.|:...:..
Mosquito   301 PVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSADRAADMHRENMKKKRREMEQASLDAASDL 365

  Fly   372 ----IKSTLTPRPARRQIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNL 432
                ..:|...:|..|..|..|:.| :.|.|.............|           ::|:..|..
Mosquito   366 LDTDSNATFAMKPLVRHPGDPLALE-KLRQCEVHMQAPKRPNCCR-----------SWLSKFPTS 418

  Fly   433 PIIRTECAEADTVSICSARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLA 497
            |..:..|.....   ||            :.|:                 ||..||..||.:|..
Mosquito   419 PFKKVPCLGRGQ---CS------------RSKR-----------------IDVISRITFPLVFAL 451

  Fly   498 FNALYW-TFVY 507
            ||.:|| |:::
Mosquito   452 FNLVYWSTYLF 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	135/493 (27%)
GluClalpha	XP_061519540.1	None