DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SecCl and NtR

DIOPT Version :9

Sequence 1:	NP_001261986.1	Gene:	SecCl / 39949	FlyBaseID:	FBgn0036727	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_651958.2	Gene:	NtR / 43935	FlyBaseID:	FBgn0029147	Length:	585	Species:	Drosophila melanogaster

Alignment Length:	313	Identity:	62/313 - (19%)
Similarity:	126/313 - (40%)	Gaps:	66/313 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 QQTQLIQRLTHV-CRYDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRF 106
            ::|:..:.|:|: .:.:....|....|    :....:||...|   ...|.|||.:||  :.:.:
  Fly   212 EETKTEKLLSHLNIQAENASMPANLSS----ISFHFQTRSLAY---EQTSSLLQTRMH--MMMHW 267

  Fly   107 QDKRLAYKA--FNRSDNILGQKHLSERLWLPHIFFAN---ERESSILGTDEKDVLTSLSPEGNV- 165
            :|.||.:|.  |...::.   :|...|:|.||:...|   :....:|.:.|..|..:    |::
  Fly   268 RDSRLVWKPEDFGSLESF---EHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYAN----GSIT 325

  Fly   166 IISTRMQASLYCWMNFQKFPFDQQFCSTVL----ESWMYNTSDLILEWEPHTPISFDPEMRLTEY 226
            :.:..:|.:.:|..:.:.:|.::..|...|    :....|.: ||.: :...||:.:..:
  Fly   326 LYAQNLQLASWCVDSARNWPSERVTCDIELGLNGQEGQENVA-LIYD-DQRKPIAPNEHV----- 383

  Fly   227 NMAQFWHNT--TIVQSDGDNLRH----GAFAGNYSSLSFTVNLKREIGFYLLDYYLP-------- 277
            |....|..|  ::|..:.|:.|.    |........::....|:|...||:..:|||
  Fly   384 NTPSGWSFTQMSVVLVENDSQRRYNPKGMMQKMTGDVAIEFTLQRNRSFYMTVFYLPLIACQMFL 448

  Fly   278 ------------SMMIVAI---SWVSFWLQADASP---PRIMLGTSTMLSFIT 312
                        |::::|:   :|...::...|||   |.:|.....::...|
  Fly   449 ILSFVLRSTRRSSLILIALLIAAWGLMYMTRYASPHYVPPMMTAYKVIMMTTT 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	62/313 (20%)
		Neur_chan_LBD	44..267	CDD:280998	48/239 (20%)
		Neur_chan_memb	275..503	CDD:280999	12/64 (19%)
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
NtR	NP_651958.2	Neur_chan_LBD	212..429	CDD:280998	47/239 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100