Protein Alignment SecCl and pHCl-2

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_651861.1
• Gene: pHCl-2 / 43703
• FlyBaseID: FBgn0039840
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 502
• Identity: 240/502 - (47%)
• Similarity: 324/502 - (64%)
• Gaps: 38/502 - (7%)

  Fly    23 SVGVKAEE---EECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYDSDGKRLPIVVKTRIYVY 84
            ||.:...:   ..|||:.:|.|:...:|:.|||..|||||:..|..::.||:.:|:.:..|.|:|
  Fly    48 SVSINLSQSTVNNCPSLKNAESMALMELLTRLTAPCRYDRMVPPVVHNKDGEEVPMDIYARFYIY 112

  Fly    85 FLQNLNSDLLQFKMHALLQLRFQDKRLAYKAF--NRSDNILGQKHLSERLWLPHIFFANERESSI 147
            .::||:|..|||.:..|||||:.|.|||:.::  ||...|:|:..|.:.||:||||..||:.|::
  Fly   113 VMKNLDSSDLQFTVQGLLQLRYLDPRLAFSSYLPNRRQPIMGESELKKMLWVPHIFLTNEQASTV 177

  Fly   148 LGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTSDLILEWEPH 212
            |||..||.|||:.|.|.|:.|||:||:|||||||||||||:|.|.|.||||||||:.:.|.||..
  Fly   178 LGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQKCKTTLESWMYNTTLVQLHWETD 242

  Fly   213 TPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKREIGFYLLDYYLP 277
            .|:|||.:::|||||:....:|.:|..|:...:.||:..||||.:||||.|.||:|:|::||:||
  Fly   243 NPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEGNYSIISFTVLLTREVGYYVIDYFLP 307

  Fly   278 SMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIF 342
            |:|||.|||||||||||.:|.|..||.:|:|||||||.||..||.||||:.:||||||.||.|||
  Fly   308 SIMIVTISWVSFWLQADQTPARTTLGCTTLLSFITLSLSQENNLMKVSYVTMSEVWFLVCTIFIF 372

  Fly   343 GSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLSNESRARSCSSLDNIVSS 407
            |||||||||||||||..:::|||..:|||:|||..|...:.:..|....:|...:.|:     :|
  Fly   373 GSLVEFAFVNTIWRRNNDLQLKKRTTKYIVKSTFVPHLKKHRRHGYRRTDSTMSTMST-----TS 432

  Fly   408 TESVRNGNGTVNQGFNNYLTVHPNLPII------RTECA----EADTVSICSARTNNDHIVDVDK 462
            .:.....|.||       :|:  ..|||      |.:.|    |.|..|...:.         |.
  Fly   433 MDKTCGPNNTV-------ITI--ETPIIIGGSLSREDSAISLDEQDETSTSESS---------DS 479

  Fly   463 DKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFVYVL 509
            .|:....||.||||:|:::||||:.||:||..|:.||||:||.||.|
  Fly   480 SKEKPAQTFATMTPKEVSLWIDRKMRFVFPLSFIVFNALFWTLVYCL 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	229/473 (48%)
pHCl-2	NP_651861.1	LIC	46..522	CDD:455710	236/496 (48%)