Protein Alignment SecCl and nAChRalpha1

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001262916.1
• Gene: nAChRalpha1 / 42918
• FlyBaseID: FBgn0000036
• Length: 597
• Species: Drosophila melanogaster
• Alignment Length: 314
• Identity: 78/314 - (24%)
• Similarity: 129/314 - (41%)
• Gaps: 43/314 - (13%)

  Fly    57 YDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDN 121
            |:||.||...:||  ||.:.:..|:......||.:.::  ..:..::..:.|.:|.:    ..|:
  Fly    36 YNRLIRPVGNNSD--RLTVKMGLRLSQLIDVNLKNQIM--TTNVWVEQEWNDYKLKW----NPDD 92

  Fly   122 ILGQKHL---SERLWLPHIFFANERESSILGTDEKDVLTS--LSPEGNVIISTRMQASLYCWMNF 181
            ..|...|   ||.:|||.|...|..:    |..|..::|.  |...|.|:.........:|.::.
  Fly    93 YGGVDTLHVPSEHIWLPDIVLYNNAD----GNYEVTIMTKAILHHTGKVVWKPPAIYKSFCEIDV 153

  Fly   182 QKFPFDQQFCSTVLESWMYNTSDLILEWEPHTPISFDPE--MRLTEYNMAQFWHNTTIVQSDGDN 244
            :.||||:|.|.....||.|:...:.|.....|..|.:.|  :.|.:|.::..|          |.
  Fly   154 EYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADSDNIEVGIDLQDYYISVEW----------DI 208

  Fly   245 LRHGAFAGN---------YSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRI 300
            :|..|....         |..:.|.:.|:|:..||.::..:|.:.|..:|.:.|:|.:| |..:|
  Fly   209 MRVPAVRNEKFYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSD-SGEKI 272

  Fly   301 MLGTSTMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTI 354
            .|..|.:||........::.:|..|.    .|..||........||..:.|.||
  Fly   273 SLCISILLSLTVFFLLLAEIIPPTSL----TVPLLGKYLLFTMMLVTLSVVVTI 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	78/314 (25%)
		Neur_chan_LBD	44..267	CDD:280998	54/225 (24%)
		Neur_chan_memb	275..503	CDD:280999	22/80 (28%)
nAChRalpha1	NP_001262916.1	Neur_chan_LBD	25..240	CDD:280998	54/225 (24%)
		LIC	27..530	CDD:273305	78/314 (25%)
		Neur_chan_memb	247..530	CDD:280999	22/81 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447286
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030