Protein Alignment SecCl and gabra6a

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_005173169.1
• Gene: gabra6a / 393704
• ZFINID: ZDB-GENE-040426-1692
• Length: 435
• Species: Danio rerio
• Alignment Length: 471
• Identity: 125/471 - (26%)
• Similarity: 197/471 - (41%)
• Gaps: 104/471 - (22%)

  Fly    57 YDRLERPFEYDSDGKRLPIV-VKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSD 120
            ||...||      |..:.:. |||.|:|.....::...::|.|....:..:.|:||   ||....
Zfish    38 YDNRLRP------GSGVSVTEVKTDIFVTSFGPVSDVNMEFTMDMFFRQMWVDERL---AFQGPI 93

  Fly   121 NILG-QKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKF 184
            .||. ...:.:::|.|..||.|.|:|........:.|..:...|.|..:.|:..|..|.|..:.|
Zfish    94 EILPLNNRMVDKIWTPDTFFRNARKSLAHNMTSPNKLFRIMQNGTVFYTMRLTVSAVCPMVLRDF 158

  Fly   185 PFDQQFCSTVLESWMYNTSDLILEWEP--HTPISFDPEMRLTEYNMAQFWHNTTIVQSD--GDNL 245
            |.|...|.....|:.|...:::..|..  ...:.|.||             :::::|.|  |..|
Zfish   159 PMDGHTCPLYFGSYAYTNREIVYTWRKGLEASVDFPPE-------------SSSLLQYDLLGQTL 210

  Fly   246 RHGAF---AGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTM 307
            ....:   .|.||.......|:|::|::|:..|:|.:|:|.:|.||||:..::.|.|.:.|.:|:
Zfish   211 FTETYKFSTGLYSVQVVHFYLQRKLGYHLIQTYIPLIMVVVLSQVSFWINKESVPARTVAGITTV 275

  Fly   308 LSFITLSSSQSKNLPKVSYIKVSEVWFLG-CTFFIFGSLVEFAFVN---TIWRRKENIELKKVNS 368
            |:..|||.|...:||||||....: ||:. |..|:..:|||||.||   |:...:||.:|
Zfish   276 LTMTTLSISARSSLPKVSYATAMD-WFIAVCFAFVASALVEFAAVNYYATLEANRENHKL----- 334

  Fly   369 KYIIKSTLTPRPARRQIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLP 433
                     ||       ||:. ||:|                        ||.::    .|..|
Zfish   335 ---------PR-------GSIV-ESQA------------------------QGSDD----EPESP 354

  Fly   434 IIRTECAEADTVSICSARTNNDHIVDVDKDKKDTPPTF---TTMTPQEI---AMWIDRRSRFLFP 492
                   ::||    ||.:.......|.:..:...|.|   :...|..:   ...||:.||.|||
Zfish   355 -------QSDT----SAYSRKRRGYPVSEAPRTRVPIFLQGSAFPPNMMLAGTSAIDKYSRILFP 408

  Fly   493 AMFLAFNALYWTFVYV 508
            ..|..||.:|| ::|:
Zfish   409 LAFGIFNLVYW-YIYL 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	124/466 (27%)
gabra6a	XP_005173169.1	LIC	2..422	CDD:455710	124/468 (26%)
		LGIC_ECD	37..234	CDD:475126	51/217 (24%)