Protein Alignment SecCl and lgc-36

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001023766.1
• Gene: lgc-36 / 3565335
• WormBaseID: WBGene00008551
• Length: 536
• Species: Caenorhabditis elegans
• Alignment Length: 583
• Identity: 128/583 - (21%)
• Similarity: 234/583 - (40%)
• Gaps: 141/583 - (24%)

  Fly     4 LHLSEIFWITLI------LVLSI------WTSVGVKAEEEECPSMADAGSL---------QQTQL 47
            ||....|.::||      ::||:      :|...||        ....||.         ::..:
 Worm     2 LHRISKFTVSLIIFFISTIILSVCGNELKFTIENVK--------FRSPGSFRIKRTVHPKREKGV 58

  Fly    48 IQRLTHVC-----RYDRLERP-FEYDSDGKRLPIVVKTRIYV-YFLQNLN--SDLLQ-FKMHALL 102
            .|.:||:.     .||:..|| |   :.||      .|::|: .|::.:.  |||.. :..:...
 Worm    59 AQNVTHLLNNVLKNYDQHFRPGF---NSGK------PTKVYIDLFIRTMGPVSDLFNTYSFNCYF 114

  Fly   103 QLRFQDKRLAYKAFNRSDNILGQKHLS------ERLWLPHIFFANERESSILGTDEKDVLTSLSP 161
            :.::.|.||   .||.|.  :|.:.||      :::|.|..:|.|...|.:.|....:.|..|.|
 Worm   115 RQKWTDDRL---HFNNSG--IGFRQLSLSMAMLDKIWKPDTYFWNGAGSYVHGITTSNRLVRLEP 174

  Fly   162 EGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTSDLILEW-----EPHTPISFDPEM 221
            :|.::.|:|:.....|.|:..::|.|:|.|..|:.|:.|::.::..:|     :....|.::...
 Worm   175 DGTILYSSRITVKAKCQMDMSRYPLDKQACRLVIGSYAYSSDEVQYKWRIMGDDNGVKIDYESIA 239

  Fly   222 RLTEYNMAQF--WHNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAI 284
            .|.:::::.|  :....|.:..           .||:|.......|..|::|:::|:|..::|.:
 Worm   240 DLPQFSLSGFKVYKPANITRDK-----------EYSALEVRFYFDRHFGYFLMNFYVPCALVVLL 293

  Fly   285 SWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFA 349
            .||:|:.:.:|:..||.:|.:.:|:.:.:|.....:.|||......||:...|.......:|||.
 Worm   294 CWVAFFTKREATAERIGIGITNVLTIVLISMDSKSDSPKVDSPTALEVFIWICYLTHLICMVEFT 358

  Fly   350 FVNTIWRRKENI------ELKKVNSKYIIKS--------TLTPRPARR------QIGGSLSNESR 394
            .|:  :..|.|.      |:::...:.|||.        ...|...||      .|...|.|:::
 Worm   359 VVH--YHTKYNTGDPEIQEVERERLRQIIKQIPKNTNNRATEPTFRRRNAALPVSIARPLPNKTK 421

  Fly   395 ARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICSARTNN----- 454
            .............|||::    .:.:..|...|.|..:         ..::::.|.|..|
 Worm   422 RFMSVRQPKKSEQTESIQ----LMRKISNMESTTHNEV---------ESSLNLESIRQENVGWRL 473

  Fly   455 -----DHIVDVDKDKKDTPPTFTTMTP----QEIAMWIDRRSRFLFPAMFLAFNALYWTFVYV 508
                 ||.:..|              |    |.....||:.|..:.|.:|:...|||:.| ||
 Worm   474 YYWMIDHNIKTD--------------PFGVAQNSTSRIDKISVIVAPLIFILTIALYYDF-YV 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	113/518 (22%)
		Neur_chan_LBD	44..267	CDD:280998	55/245 (22%)
		Neur_chan_memb	275..503	CDD:280999	55/261 (21%)
lgc-36	NP_001023766.1	LIC	48..520	CDD:273305	114/526 (22%)
		Neur_chan_LBD	63..272	CDD:280998	53/233 (23%)
		Neur_chan_memb	284..511	CDD:280999	53/255 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810