Protein Alignment SecCl and gabrb2a

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001019558.2
• Gene: gabrb2a / 336252
• ZFINID: ZDB-GENE-030131-8196
• Length: 519
• Species: Danio rerio
• Alignment Length: 525
• Identity: 131/525 - (24%)
• Similarity: 234/525 - (44%)
• Gaps: 125/525 - (23%)

  Fly    57 YDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDN 121
            ||...||   |..|  .|:.|...|.:..:..::...:.:.:....|..::||||:|.....  |
Zfish    46 YDIRLRP---DFGG--APVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYSEIPL--N 103

  Fly   122 ILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPF 186
            :.....::::||:|..:|.|:::|.:.|...|:.:..|.|:|.|:...|:..:..|.|:.:::|.
Zfish   104 LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPL 168

  Fly   187 DQQFCSTVLESWMYNTSDLILEWEPHTPISFD-----------PEMRLTEYNMAQFWHNTTIVQS 240
            |:|.|:..:||:.|.|.|:...|.     ..|           |:..:.:|.:.    :..:|.|
Zfish   169 DEQNCTLEIESYGYTTDDIEFYWR-----GGDGAVSGVERIELPQFSIVDYKLI----SKNVVFS 224

  Fly   241 DGDNLRHGAFAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTS 305
                      .|:|..||.:..|||.||:::|..|:||::|..:||||||:..|||..|:.||.:
Zfish   225 ----------TGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGIT 279

  Fly   306 TMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIW------RRKE----- 359
            |:|:..|:::...:.|||:.|:|..:::.:||..|:|.:|:|:||||.|:      |:|:
Zfish   280 TVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKAAEKA 344

  Fly   360 ----NIELKKVNSKYIIKS------TLTPRPARRQIGG------SLSNESRA------RSCSSLD 402
                |.:|:...:|:::.|      .|..|..:|:|.|      .:..|..|      |...:.|
Zfish   345 ATANNEKLRPDPNKWLVGSVVQRDDALYARMKQREIDGYDSMWDPIFAEDAALGLGDQRLKMTPD 409

  Fly   403 NIVSSTESVRN--GNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICSARTNNDH--------- 456
            :|..:|..::|  |...:::|..:     |...::..:.:.........||.|..|
Zfish   410 DIRLTTVEMKNEMGPSDLSRGLGD-----PRSTMLAYDSSTLQYRRAAMARQNYGHSALERHATQ 469

  Fly   457 ------------------IVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYW 503
                              :.||:.                    ||:.||.:||.:|..||.:||
Zfish   470 KKSRLRRRASQLKVNIPDLSDVNS--------------------IDKWSRMIFPTLFSFFNIVYW 514

  Fly   504 TFVYV 508
            .: ||
Zfish   515 LY-YV 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	129/520 (25%)
		Neur_chan_LBD	44..267	CDD:280998	53/220 (24%)
		Neur_chan_memb	275..503	CDD:280999	71/289 (25%)
gabrb2a	NP_001019558.2	LIC	7..517	CDD:273305	129/522 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810