Protein Alignment SecCl and Gabrr3

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001074659.1
• Gene: Gabrr3 / 328699
• MGIID: 3588203
• Length: 464
• Species: Mus musculus
• Alignment Length: 524
• Identity: 136/524 - (25%)
• Similarity: 246/524 - (46%)
• Gaps: 99/524 - (18%)

  Fly    11 WITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQL------------IQRLTHVCRYDRLERP 63
            ||||:|..|     .:|...::|.|......:::|::            .::|.|:..:|...||
Mouse    14 WITLMLDAS-----AIKKPHQQCLSSPKQTRIRETRMRKDDLTKVWHPKREQLLHIEDHDFSTRP 73

  Fly    64 FEYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHL 128
            ....|     |:.|...:.|..:.:::...:.|.|...|:..::|:||::.: ..:.::...:.|
Mouse    74 GFGGS-----PVPVGIDVQVESIDSISEVNMDFTMTFYLRHYWKDERLSFPS-TTNKSMTFDRRL 132

  Fly   129 SERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCST 193
            .:::|:|.|||.:.:.|.|..|..::::..:.|:|||:.|.|:..|..|:|:|.:||.|.|.||.
Mouse   133 LQKIWVPDIFFVHSKRSFIHDTTVENIMLRVHPDGNVLFSLRITVSAMCFMDFSRFPLDTQNCSL 197

  Fly   194 VLESWMYNTSDLILEWEPHTPISFDPEMR--LTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSS 256
            .|||:.||..||:|.|: |...|.:.|.|  |:::.:.:|        |....|...:..|.|..
Mouse   198 ELESYAYNEEDLMLYWK-HGNKSLNTEERISLSQFFIEEF--------SASSGLAFYSSTGWYYR 253

  Fly   257 LSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNL 321
            |.....|:|.:.|::|..|.|:|::|.:||||||:...|.|.|:.||.:|:|:..|:.:..|.::
Mouse   254 LFINFVLRRHVFFFVLQTYFPAMLMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTVVTGVSASM 318

  Fly   322 PKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIG 386
            |:|||:|..:|:....:.|:|.|::|:|.||.:...:|..:|.:                |.:|.
Mouse   319 PQVSYVKAVDVYMWVSSLFVFLSVIEYATVNYLTTVEEWKQLNR----------------RGKIS 367

  Fly   387 GSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTE-----CAEADTVS 446
            |....:  |....:.|.....:|:      .|:|   ...::|.....:.|:     ||::..:.
Mouse   368 GMYHID--AVQAMAFDGCYHDSET------DVDQ---TSFSLHSEEDSMSTKFTGSPCADSSQIK 421

  Fly   447 ICSARTN-------NDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWT 504
            ..|...|       |:|::|          |:               ||.:||.:::.||..||.
Mouse   422 RKSLGGNVGRIILENNHVID----------TY---------------SRIVFPTVYIIFNLFYWG 461

  Fly   505 FVYV 508
             :||
Mouse   462 -IYV 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	125/487 (26%)
		Neur_chan_LBD	44..267	CDD:280998	63/236 (27%)
		Neur_chan_memb	275..503	CDD:280999	58/239 (24%)
Gabrr3	NP_001074659.1	LIC	58..463	CDD:273305	124/472 (26%)
		Neur_chan_LBD	59..264	CDD:280998	62/219 (28%)
		Neur_chan_memb	271..460	CDD:280999	58/240 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810