Protein Alignment SecCl and Gabrg2

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001380704.1
• Gene: Gabrg2 / 29709
• RGDID: 61966
• Length: 474
• Species: Rattus norvegicus
• Alignment Length: 542
• Identity: 116/542 - (21%)
• Similarity: 215/542 - (39%)
• Gaps: 136/542 - (25%)

  Fly    11 WITLILVLSIWTSVGVKAEEEECPSMAD-----------AGSLQQTQLIQRLTHVCRYDRLERPF 64
            ||  :|:||::.....:..:::....|.           .|.:  |.::..|..  .||...||
  Rat    25 WI--LLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDV--TVILNNLLE--GYDNKLRP- 82

  Fly    65 EYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAY----KAFNRSDNILGQ 125
              |...|  |.::.|.:||..:..:|:..:::.:.......:.|:||.:    |....:.|::|
  Rat    83 --DIGVK--PTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVG- 142

  Fly   126 KHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQF 190
                 ::|:|..||.|.:::........:.:..:..:|.|:.:.|:.....|.:....||.|:..
  Rat   143 -----KIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHS 202

  Fly   191 CSTVLESWMYNTSDLILEWE-PHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNY 254
            |.....|:.|...:::.:|: ....:......||.:::.....:.|.:|::.         :|:|
  Rat   203 CPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTT---------SGDY 258

  Fly   255 SSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSK 319
            ..:|...:|.|.:|::.:..|:|..:||.:||||||:..||.|.|..||.:|:|:..|||:...|
  Rat   259 VVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARK 323

  Fly   320 NLPKVSYIKVSEVWFLGCTFFIFGSLVEFA----FVNTIWRRKENIELKKVNSKYIIKSTLTPRP 380
            :||||||:...:::...|..|:|.:|||:.    ||:.....|:. :.||.|
  Rat   324 SLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK-DKKKKN------------- 374

  Fly   381 ARRQIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTV 445
                                                                |::|....:|.|:
  Rat   375 ----------------------------------------------------PLLRMFSFKAPTI 387

  Fly   446 SI----CSARTNN-DHIVDVDK-------DKKDTPPTFTTMTPQEIAMW-----------IDRRS 487
            .|    .:.:.|| .|:.:.|:       |.||....|..........|           :|..:
  Rat   388 DIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYA 452

  Fly   488 RFLFPAMFLAFNALYW-TFVYV 508
            |..||..|..||.:|| :::|:
  Rat   453 RIFFPTAFCLFNLVYWVSYLYL 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	108/494 (22%)
		Neur_chan_LBD	44..267	CDD:280998	44/227 (19%)
		Neur_chan_memb	275..503	CDD:280999	61/254 (24%)
Gabrg2	NP_001380704.1	LIC	68..471	CDD:273305	107/490 (22%)
		LGIC_ECD_GABAAR_G	89..270	CDD:349801	34/195 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810