Protein Alignment SecCl and Gabra5

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_058991.2
• Gene: Gabra5 / 29707
• RGDID: 61859
• Length: 464
• Species: Rattus norvegicus
• Alignment Length: 461
• Identity: 121/461 - (26%)
• Similarity: 204/461 - (44%)
• Gaps: 87/461 - (18%)

  Fly    57 YDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRS-- 119
            ||...||    ..|:|: ..|:|.|||.....::...:::.:....:..::|:||.:|...:.
  Rat    60 YDNRLRP----GLGERI-TQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLP 119

  Fly   120 -DNILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQK 183
             :|:|..|     :|.|..||.|.::|........:.|..|..:|.::.:.|:..|..|.|..:.
  Rat   120 LNNLLASK-----IWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLED 179

  Fly   184 FPFDQQFCSTVLESWMYNTSDLILEW---EPHTPISFDPEMRLTEYN-MAQFWHNTTIVQSDGDN 244
            ||.|...|.....|:.|..|:::..|   ...:.:..:...||.:|: |.|......|..|.|:
  Rat   180 FPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGE- 243

  Fly   245 LRHGAFAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLS 309
                     |:.::...:|||:||::::..|||.:|.|.:|.|||||..::.|.|.:.|.:|:|:
  Rat   244 ---------YTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLT 299

  Fly   310 FITLSSSQSKNLPKVSYIKVSEVWFLG-CTFFIFGSLVEFAFVNTI------WRRKENIELKKVN 367
            ..|||.|...:||||:|....: ||:. |..|:|.:|:|||.||..      |..|:.:|..|:.
  Rat   300 MTTLSISARNSLPKVAYATAMD-WFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAAKIK 363

  Fly   368 SKYIIKSTLTPRPARRQIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNL 432
            .|            .|::   :.|:              ||.:...|.          ||..||:
  Rat   364 KK------------EREL---ILNK--------------STNAFTTGK----------LTHPPNI 389

  Fly   433 PIIRTECAEADTVSICSARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLA 497
            |..:......:.|...|.|.:.:   ...:.||    |:.:::.      ||:.||.:||.:|..
  Rat   390 PKEQLPGGTGNAVGTASIRASEE---KTSESKK----TYNSISK------IDKMSRIVFPILFGT 441

  Fly   498 FNALYW 503
            ||.:||
  Rat   442 FNLVYW 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	121/461 (26%)
		Neur_chan_LBD	44..267	CDD:280998	51/216 (24%)
		Neur_chan_memb	275..503	CDD:280999	66/234 (28%)
Gabra5	NP_058991.2	LIC	15..450	CDD:273305	121/461 (26%)
		LGIC_ECD_GABAAR_A5	58..256	CDD:349839	50/215 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	382..414		8/44 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810