Protein Alignment SecCl and Gabrr2

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_038965308.1
• Gene: Gabrr2 / 29695
• RGDID: 61902
• Length: 491
• Species: Rattus norvegicus
• Alignment Length: 446
• Identity: 123/446 - (27%)
• Similarity: 214/446 - (47%)
• Gaps: 68/446 - (15%)

  Fly    70 GKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAY-KAFNRSDNILGQKHLSERLW 133
            |..:|:.|.  :.|..|.:::...:.|.|...|:..::|:|||: .:.|||....|:  |.:::|
  Rat   100 GPAIPVGVD--VQVESLDSISEVDMDFTMTLYLRHYWRDERLAFPSSSNRSMTFDGR--LVKKIW 160

  Fly   134 LPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESW 198
            :|.:||.:.:.|....|...:::..:.|:|:|:.|.|:..:..|.|:|..||.|.|.||..|||:
  Rat   161 VPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHFPLDSQTCSLELESY 225

  Fly   199 MYNTSDLILEWE-PHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTVN 262
            .|...||:|.|: ....:..|.::.|::: :.|.:|.|:       .|...:..|.|:.|.....
  Rat   226 AYTDEDLMLYWKNGDESLKTDEKISLSQF-LIQKFHTTS-------RLAFYSSTGWYNRLYINFT 282

  Fly   263 LKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYI 327
            |:|.|.|:||..|.|:.::|.:||||||:...|.|.|:.||..|:|:..|:.:..:.::|:||||
  Rat   283 LRRHIFFFLLQTYFPATLMVMLSWVSFWIDHRAVPARVSLGIMTVLTMSTIITGVNASMPRVSYI 347

  Fly   328 KVSEVWFLGCTFFIFGSLVEFAFVN---TIWRRKENIELKKVNSKY------IIKSTLTPRPARR 383
            :..:::......|:|.|::|:|.||   |:..:||    :|:..|:      :...|:|
  Rat   348 RAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQEQKE----RKLRDKFPCTCGMLHSRTMT------ 402

  Fly   384 QIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSIC 448
             :.||.| ||.|.|.:.........|..|.....|:...|:.||......:::.:..    :.|
  Rat   403 -LDGSYS-ESEANSLAGYPRSHILPEEERQDKIVVHLALNSELTSSRKKGLLKGQMG----LYI- 460

  Fly   449 SARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWT 504
               ..|.|.                         ||:.||.:|||.::.||.:||:
  Rat   461 ---FQNTHA-------------------------IDKYSRLIFPAFYIVFNLIYWS 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	123/446 (28%)
		Neur_chan_LBD	44..267	CDD:280998	56/198 (28%)
		Neur_chan_memb	275..503	CDD:280999	61/236 (26%)
Gabrr2	XP_038965308.1	LIC	87..490	CDD:273305	123/446 (28%)
		LGIC_ECD_GABAAR_rho	102..287	CDD:349806	55/196 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810