Protein Alignment SecCl and Gabrr1

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_058987.3
• Gene: Gabrr1 / 29694
• RGDID: 61900
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 486
• Identity: 127/486 - (26%)
• Similarity: 234/486 - (48%)
• Gaps: 71/486 - (14%)

  Fly    28 AEEEECPSMADAGSLQQTQLI--QRLTHVCRYDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLN 90
            |.::..|.:..:..:.::.|.  ::|..:..:|...||   ...|..:|:.|.  :.|..|.:::
  Rat    54 AHKQGSPILKRSSDITKSPLTKSEQLLRIDDHDFSMRP---GFGGPAIPVGVD--VQVESLDSIS 113

  Fly    91 SDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSERLWLPHIFFANERESSILGTDEKDV 155
            ...:.|.|...|:..::|:||::.:.|.. ::.....|.:::|:|.:||.:.:.|.|..|...:|
  Rat   114 EVDMDFTMTLYLRHYWKDERLSFPSTNNL-SMTFDGRLVKKIWVPDMFFVHSKRSFIHDTTTDNV 177

  Fly   156 LTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTSDLILEWEP-HTPISFDP 219
            :..:.|:|.|:.|.|:..:..|.|:|.:||.|.|.||..:||:.|...||:|.|:. :..:..|.
  Rat   178 MLRVQPDGKVLYSLRVTVTAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDE 242

  Fly   220 EMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAI 284
            .:.|:::.:.:| |.||       .|...:..|.|:.|.....|:|.|.|:||..|.|:.::|.:
  Rat   243 RISLSQFLIQEF-HTTT-------KLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVML 299

  Fly   285 SWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFA 349
            ||||||:...|.|.|:.||.:|:|:..|:.:..:.::|:|||||..:::......|:|.|::|:|
  Rat   300 SWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYA 364

  Fly   350 FVN---TIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLSNESRARSCSSLDNIVSSTESV 411
            .||   |:..|||    :|:..|......| |:|....:..|.|
  Rat   365 AVNYLTTVQERKE----RKLREKISCTCGL-PQPRGVMLDSSYS--------------------- 403

  Fly   412 RNGNGTVNQGFNNYLTVH---PNLPIIRTECAEADTVSICSARTNNDHIVDVDKDKKDTPPTFTT 473
               :|.||. ...|:..:   |:..:::        :::.|.|.:        ..:|....::.:
  Rat   404 ---DGEVND-LGGYMPENGEKPDRMMVQ--------LTLASERGS--------PQRKSQRGSYVS 448

  Fly   474 MTPQEIAMWIDRRSRFLFPAMFLAFNALYWT 504
            |.....|  ||:.||.:|||.::.||.:||:
  Rat   449 MRINTHA--IDKYSRIIFPAAYILFNLIYWS 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	125/471 (27%)
		Neur_chan_LBD	44..267	CDD:280998	59/225 (26%)
		Neur_chan_memb	275..503	CDD:280999	60/233 (26%)
Gabrr1	NP_058987.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..67		2/12 (17%)
		LIC	76..479	CDD:273305	124/464 (27%)
		LGIC_ECD_GABAAR_rho	97..282	CDD:349806	53/195 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810