Protein Alignment SecCl and GABRD

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_016856425.1
• Gene: GABRD / 2563
• HGNCID: 4084
• Length: 687
• Species: Homo sapiens
• Alignment Length: 464
• Identity: 118/464 - (25%)
• Similarity: 201/464 - (43%)
• Gaps: 113/464 - (24%)

  Fly    74 PIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILG-QKHLSERLWLPHI 137
            |:.|...:.|..:.:::...:::.|...|...::|.||:|   |.::..|| .....::||||..
Human   298 PVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSY---NHTNETLGLDSRFVDKLWLPDT 359

  Fly   138 FFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNT 202
            |..|.:.:.......::.|..|.|:|.::.|.|:.:::.|.|:..|:|.|:|.|...|||:.|::
Human   360 FIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYPMDEQECMLDLESYGYSS 424

  Fly   203 SDLILEW-EPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKRE 266
            .|::..| |....|....:::|.::.:..:...|.::     |.:.   ||.:..||...:|:|.
Human   425 EDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELM-----NFKS---AGQFPRLSLHFHLRRN 481

  Fly   267 IGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSE 331
            .|.|::..|:||:::||:||||||:...|.|.|:.||.:|:|:..||..|...:||:.|.||..:
Human   482 RGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRASAIKALD 546

  Fly   332 VWFLGCTFFIFGSLVEFAFV--NTIWRRKENIELK--------KVNSKYIIKS----------TL 376
            |:|..|..|:|.:|||:||.  |..:|:|:..::|        .|.:..::.|          .:
Human   547 VYFWICYVFVFAALVEYAFAHFNADYRKKQKAKVKVSRPRAEMDVRNAIVLFSLSAAGVTQELAI 611

  Fly   377 TPRPAR---------RQIG---GSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVH 429
            :.|..|         |.:|   |....|..|||               .|.|.:.
Human   612 SRRQRRVPGNLMGSYRSVGVETGETKKEGAARS---------------GGQGGIR---------- 651

  Fly   430 PNLPIIRTECAEADTVSICSARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAM 494
                 .|....:|||                                      ||..:|.:|||.
Human   652 -----ARLRPIDADT--------------------------------------IDIYARAVFPAA 673

  Fly   495 FLAFNALYW 503
            |.|.|.:||
Human   674 FAAVNVIYW 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	118/464 (25%)
		Neur_chan_LBD	44..267	CDD:280998	48/194 (25%)
		Neur_chan_memb	275..503	CDD:280999	66/259 (25%)
GABRD	XP_016856425.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810