Protein Alignment SecCl and Gabrb2

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_008765857.1
• Gene: Gabrb2 / 25451
• RGDID: 2650
• Length: 506
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 133/499 - (26%)
• Similarity: 229/499 - (45%)
• Gaps: 87/499 - (17%)

  Fly    57 YDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDN 121
            ||...||   |..|.  |:.|...|.:..:..::...:.:.:....|..::||||:|.....  |
  Rat    47 YDIRLRP---DFGGP--PVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPL--N 104

  Fly   122 ILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPF 186
            :.....::::||:|..:|.|:::|.:.|...|:.:..|.|:|.|:...|:..:..|.|:.:::|.
  Rat   105 LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPL 169

  Fly   187 DQQFCSTVLESWMYNTSDLILEWEPH-------TPISFDPEMRLTEYNMAQFWHNTTIVQSDGDN 244
            |:|.|:..:||:.|.|.|:...|...       |.|.. |:..:.:|.:.    ...:|.|
  Rat   170 DEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIEL-PQFSIVDYKLI----TKKVVFS---- 225

  Fly   245 LRHGAFAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLS 309
                  .|:|..||.:..|||.||:::|..|:||::|..:||||||:..|||..|:.||.:|:|:
  Rat   226 ------TGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLT 284

  Fly   310 FITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIW------RRKE--------N 360
            ..|:::...:.|||:.|:|..:::.:||..|:|.:|:|:|.||.|:      |:|:        |
  Rat   285 MTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAANAN 349

  Fly   361 IELKKVNSKYIIKSTLTPRPARRQIGGSLSNESRAR-----SCSSLD---NIVSSTESVRNGNGT 417
            .|..:::...|....:.....:.|   ||.:.:|..     |...:|   ||:.||..::|...|
  Rat   350 NEKMRLDVNKIFYKDIKQNRTQYQ---SLWDPTRWTTYYHFSLYMMDPHENILLSTLEIKNEMAT 411

  Fly   418 VN--QGFNNYLTVHPNLPIIRTECAEADTVSICSA--------RTNNDHIVDVDKDK-------- 464
            ..  .|..:     |...::   ..:|.::....|        |...:..|...|.:
  Rat   412 SEAVMGLGD-----PRSTML---AYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQL 468

  Fly   465 KDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFVYV 508
            |.|.|..|.:..      |||.||..||.:|..||.:||.: ||
  Rat   469 KITIPDLTDVNA------IDRWSRIFFPVVFSFFNIVYWLY-YV 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	131/494 (27%)
Gabrb2	XP_008765857.1	LIC	9..504	CDD:455710	131/496 (26%)