Protein Alignment SecCl and Gabrb1

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_037088.1
• Gene: Gabrb1 / 25450
• RGDID: 2649
• Length: 474
• Species: Rattus norvegicus
• Alignment Length: 495
• Identity: 136/495 - (27%)
• Similarity: 219/495 - (44%)
• Gaps: 112/495 - (22%)

  Fly    57 YDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDN 121
            ||...||   |..|.  |:.|..||.|..:..::...:.:.:....|..::||||:|.....  |
  Rat    48 YDIRLRP---DFGGP--PVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPL--N 105

  Fly   122 ILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPF 186
            :.....::::||:|..:|.|:::|.:.|...|:.:..|.|:|.|:...|:..:..|.|:.:::|.
  Rat   106 LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPL 170

  Fly   187 DQQFCSTVLESWMYNTSDLILEWEPH-------TPISFDPEMRLTEYNM----AQFWHNTTIVQS 240
            |:|.|:..:||:.|.|.|:...|...       ..|.. |:..:.:|.|    .:|   ||
  Rat   171 DEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIEL-PQFSIVDYKMVSKKVEF---TT---- 227

  Fly   241 DGDNLRHGAFAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTS 305
                       |.|..||.:..|||.||:::|..|:||.:|..:||||||:..|||..|:.||.:
  Rat   228 -----------GAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGIT 281

  Fly   306 TMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIW--------------- 355
            |:|:..|:|:...:.|||:.|:|..:::.:||..|:|.:|:|:||||.|:
  Rat   282 TVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQ 346

  Fly   356 --RRKENIELKKVN---SKYIIKSTLTPRPARRQIGGS--LSNESRARSCS-SLDNI-------V 405
              ..|..:|:.||.   ...|:.|||   ..|.:..||  |:..|..::.. |.|:.       :
  Rat   347 SANEKNKLEMNKVQVDAHGNILLSTL---EIRNETSGSEVLTGVSDPKATMYSYDSASIQYRKPL 408

  Fly   406 SSTESVRNGNGTVNQGFNNYLTVH--PNLPIIRTECAEADTVSICSARTNNDHIVDVDKDKKDTP 468
            ||.|           ||...|..|  |....||...::        .:.....:.||:.
  Rat   409 SSRE-----------GFGRGLDRHGVPGKGRIRRRASQ--------LKVKIPDLTDVNS------ 448

  Fly   469 PTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFVYV 508
                          ||:.||..||..|..||.:||.: ||
  Rat   449 --------------IDKWSRMFFPITFSLFNVVYWLY-YV 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	134/490 (27%)
Gabrb1	NP_037088.1	LIC	9..472	CDD:273305	134/492 (27%)