Protein Alignment SecCl and Gabrp

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_666129.1
• Gene: Gabrp / 216643
• MGIID: 2387597
• Length: 440
• Species: Mus musculus
• Alignment Length: 464
• Identity: 115/464 - (24%)
• Similarity: 201/464 - (43%)
• Gaps: 90/464 - (19%)

  Fly    57 YDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDN 121
            |::..|| .:..|    |:.:...:.:..:.:::...:.:.....|:.|:.|.||.::. |:|..
Mouse    48 YNKFLRP-NFGGD----PVRIALTLDIASISSISESNMDYTATIYLRQRWTDPRLVFEG-NKSFT 106

  Fly   122 ILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPF 186
            :  ...|.|.||:|..:....::|.:......:.|..|...|.|:.:.|:..::.|.|:..|:|.
Mouse   107 L--DARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVTCNMDLSKYPM 169

  Fly   187 DQQFCSTVLESWMYNTSDLILEW-EPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAF 250
            |.|.|...||||.|:.:|:...| ..:..:.....:||.:|.:.|::...|:.|.:
Mouse   170 DTQTCKLQLESWGYDGNDVEFSWLRGNDSVRGLENLRLAQYTIQQYFTLVTVSQQE--------- 225

  Fly   251 AGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSS 315
            .|||:.|.....|:|.:.:::|:.|:||..:|.:||||||:..|:.|.|..:|.:|:||..||..
Mouse   226 TGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMI 290

  Fly   316 SQSKNLPKVS-YIKVSEVWFLGCTFFIFGSLVEFAFVN-------TIWRRKENIELKKVNSKYII 372
            ....:||..: :||..:|:...|..|:||:|:|:|..:       .:..|....:.::||...||
Mouse   291 GSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAVKDRGPAKDSEEVNITNII 355

  Fly   373 KSTLTPRPARRQIGGSLSNESRARSCSSL----DNIVSSTESVRNGNGTVNQGFNNY--LTVHPN 431
            .|             |:|:..|..|.:|:    ||:                   ||  ||:
Mouse   356 NS-------------SISSFKRKISFASIEISGDNV-------------------NYSDLTM--- 385

  Fly   432 LPIIRTECAEADTVSICSARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFL 496
                     :|........|.....|:|.          ||...|..    :||.|:.|||.:|:
Mouse   386 ---------KASDKFKFVFREKISRIIDY----------FTIQNPSN----VDRYSKLLFPLIFM 427

  Fly   497 AFNALYWTF 505
            ..|..||.:
Mouse   428 LANVFYWAY 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	115/462 (25%)
		Neur_chan_LBD	44..267	CDD:280998	49/210 (23%)
		Neur_chan_memb	275..503	CDD:280999	63/241 (26%)
Gabrp	NP_666129.1	Neur_chan_LBD	41..242	CDD:280998	49/210 (23%)
		LIC	43..437	CDD:273305	115/464 (25%)
		Neur_chan_memb	249..434	CDD:280999	63/242 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810