Protein Alignment SecCl and glra4b

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001189440.1
• Gene: glra4b / 192125
• ZFINID: ZDB-GENE-020402-2
• Length: 492
• Species: Danio rerio
• Alignment Length: 539
• Identity: 148/539 - (27%)
• Similarity: 244/539 - (45%)
• Gaps: 96/539 - (17%)

  Fly     7 SEIFWITLILVLSIWTSVG----VKAEEEECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYD 67
            |.|:.|.|.|:|..|...|    |.::|.:.||:..........|.:.:.....||...||
Zfish     3 SVIWRILLELLLVCWMFEGVIRCVFSKELKSPSVRTKPMSPSDFLDKLMGKTSGYDARIRP---- 63

  Fly    68 SDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSERL 132
             :.|..|:.|...|::....::....:.::::..|:.::.|.|||||.: ..|::.....:.:.:
Zfish    64 -NFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYKEY-PDDSLDLDPSMLDSI 126

  Fly   133 WLPHIFFANERESSI--LGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVL 195
            |.|.:|||||:.::.  :.||.|  |..:...|||:.|.|:...|.|.|:.:.||.|.|.|:..|
Zfish   127 WKPDLFFANEKGANFHEVTTDNK--LLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDTQTCTMQL 189

  Fly   196 ESWMYNTSDLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSD-GDNLRHGAFAGNYSSLSF 259
            ||:.|..:|||.:|....|:....::.|.::.:.:        :.| |...:| ...|.::.:..
Zfish   190 ESFGYTMNDLIFQWLDEGPVQVADDLMLPQFVLKE--------EKDLGYCTKH-YNTGKFTCIEV 245

  Fly   260 TVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKV 324
            ..:|:|::|:||:..|:||::.|.:||||||:..||:|.|:.||.:|:|:..|.||....:||||
Zfish   246 KFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKV 310

  Fly   325 SYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRR-KENIELKKVNSKYIIKSTLTPRPARRQIGGS 388
            ||:|..::|...|..|:|.:|:|:|.||.:.|: ||...|::.     ::.....|.|..|.|.:
Zfish   311 SYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQYKEFFRLRRK-----LRQEQRNRAASGQAGAA 370

  Fly   389 LSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICSARTN 453
               |::.:|    :|:...|.| ||....                              |||...
Zfish   371 ---ETKNKS----NNVTGGTPS-RNAQRQ------------------------------CSACAR 397

  Fly   454 NDHIVDVDKD------------KKDTP-----PTFTTMTP-----------QEIAMWIDRRSRFL 490
            .:.:...::|            ..|.|     ..|..:.|           .|.|..||..||.:
Zfish   398 EEQLASQNQDLYFPGFGIDTSLSGDGPLSEAAAMFAGLPPGHALFDIRRRFVEQAKRIDTISRAV 462

  Fly   491 FPAMFLAFNALYWTFVYVL 509
            ||..||.||..||....||
Zfish   463 FPLSFLVFNVFYWVTYKVL 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	134/493 (27%)
		Neur_chan_LBD	44..267	CDD:280998	57/225 (25%)
		Neur_chan_memb	275..503	CDD:280999	72/256 (28%)
glra4b	NP_001189440.1	LIC	5..478	CDD:273305	145/532 (27%)
		Neur_chan_LBD	47..253	CDD:280998	57/222 (26%)
		Neur_chan_memb	260..475	CDD:280999	72/257 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910