Protein Alignment SecCl and lgc-58

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001368738.1
• Gene: lgc-58 / 191637
• WormBaseID: WBGene00001587
• Length: 553
• Species: Caenorhabditis elegans
• Alignment Length: 588
• Identity: 140/588 - (23%)
• Similarity: 251/588 - (42%)
• Gaps: 131/588 - (22%)

  Fly    14 LILVLSIW-----TSVGVKAEEEE-----CPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYDS 68
            ::||.||:     .|..|:|...|     ..::.:||  :|.           ||....|.::|
 Worm     1 MLLVSSIFLLLYRNSPKVEASRSEPVPIYLDNLLNAG--RQV-----------YDNQSPPVQHD- 51

  Fly    69 DGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSERLW 133
              |....||:..:|:..:.:..:..:.|::....|..::|.|||:....|.  ::..|.:..::|
 Worm    52 --KEEVTVVELAMYIEGMSSFRTQTMDFQLDVYFQQFWRDPRLAHNETRRV--LVKDKAVLHKMW 112

  Fly   134 LPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESW 198
            .|.::|||.|.:......:.:.|..:.|:|:::..||:...:.|.:|.:|:|.|.|.|...:.|:
 Worm   113 KPDVYFANARIAEFHEVTQPNFLVWIQPDGSILYDTRISMVVVCTLNLEKWPLDSQRCHLRILSY 177

  Fly   199 MYNTSDLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSS-----LS 258
            .|.|..|:::|:...||:.:|.:.:::.::.              :|..|...||||:     ::
 Worm   178 AYTTEQLVIKWKEDEPITRNPNIAMSDMHIV--------------DLYPGLCDGNYSTGTWSCVT 228

  Fly   259 FTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPK 323
            ....:||||..:::..|:|:.:||.|||.||||..:|.|.|:.|..:|:|:..|.:::....||:
 Worm   229 AEFFVKREITHHVMQSYVPTTLIVVISWFSFWLDVEAVPARVSLAITTLLTLSTQANAARMALPE 293

  Fly   324 VSYIKVSEVWFLGCTFFIFGSLVEFAFVNTI------WRRKENIELKKVNSKYIIKS-TLTPRPA 381
            |||:|..:||...|..|:||.::||..||..      |.|.: .|:...:|...:|| ....:|:
 Worm   294 VSYMKAIDVWMGACMMFVFGVMIEFTIVNYAQRQGRKWHRTD-AEIVMASSLESVKSGNAEKKPS 357

  Fly   382 RRQIGG-------SLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPII---R 436
            |..:|.       .|....|..........::..::..:   ||:|.::|..:.....|::   :
 Worm   358 RGDLGAHARHLFLRLRTNERQHLVEDPPEQIAMNDTAYD---TVSQAYSNSFSDEEAAPVVQPPQ 419

  Fly   437 TECAEA-DTVSICSARTN----------------------------------------------- 453
            .|.||| :.|......||
 Worm   420 NEDAEAQEEVWAEQKETNLSEVWKESDPAERLAHWNEKENDASSPLMGNGRAHVRYGAAEKMKNR 484

  Fly   454 --NDH----------IVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFV 506
              ||.          |..:.|.|:: ...|..:..:..|..||:.||::||..|:.||..||  :
 Worm   485 KCNDSSRKKEKWSSAIKQIQKHKRN-GSVFGKIAGRNRAKKIDQTSRWIFPLTFIIFNLTYW--I 546

  Fly   507 YVL 509
            |.|
 Worm   547 YYL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	128/543 (24%)
lgc-58	NP_001368738.1	LIC	30..548	CDD:455710	130/556 (23%)