Protein Alignment SecCl and lgc-57

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_496306.2
• Gene: lgc-57 / 191636
• WormBaseID: WBGene00001586
• Length: 473
• Species: Caenorhabditis elegans
• Alignment Length: 521
• Identity: 131/521 - (25%)
• Similarity: 223/521 - (42%)
• Gaps: 93/521 - (17%)

  Fly    15 ILVLSIWTSVGVKAE----EEECPSMADAGSLQQ-TQLIQRLTHVCRYDRLERPFEYDSDGKRLP 74
            ||:.|:...|..:||    :|....:.:...:.. |::::|   |..|:|...|. .|.|   |.
 Worm     8 ILIYSLMQCVLGQAEFWDYDENVTQIEEDFKIDDVTRILKR---VGNYNRNAYPL-LDQD---LA 65

  Fly    75 IVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNIL-GQKHLSERLWLPHIF 138
            ..|..::|:..:.:.::..:.|::....|.::.|.||.:   |.:..|| ....|...||.|.::
 Worm    66 THVDIQMYIEGMSSFHAQSMDFQVDIYFQEKWVDHRLQH---NNTKRILVKDPKLFGLLWHPDLY 127

  Fly   139 FANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTS 203
            |||.|.:|.....:.:.|..:.|.|.|....|:..::.|..:..::|.|.|.|...:.|:.|:..
 Worm   128 FANARTASFHDVTQPNFLVWIYPNGTVWYDCRISLTVLCMQDLARYPLDSQNCGLRILSYAYDEE 192

  Fly   204 DLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAF--------AGNYSSLSFT 260
            .||:.|....|:..:..:|:.:.                 :|:|..|        .|.:||....
 Worm   193 QLIIRWNGGNPVEVNRGIRMPDM-----------------HLKHIKFYTKRDKYATGIWSSAVAE 240

  Fly   261 VNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVS 325
            .::.|||..:::..|:|:.:||.|||.||||..:|.|.|:.|..:|:|:..|.||:....||:.|
 Worm   241 FHVDREITHHIIQSYIPTSLIVIISWFSFWLDVEAVPGRVSLSITTLLTLATQSSAARMALPQAS 305

  Fly   326 YIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLS 390
            .:|..:||...|..|:|.:::||..||...|||             :::.:.||....|:...::
 Worm   306 DVKAIDVWMGTCMAFVFSAMIEFTVVNYCVRRK-------------VRTKIKPRGLSEQVHDMVA 357

  Fly   391 NESRARSCSSLDNIVSSTESV---RNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSI----- 447
            .....:...:..|...|.|..   ...|.||.:.|.            :.|..|.:..|:
 Worm   358 QYREKKDKFNNGNCEISYEMALQPNEDNATVQRNFE------------KKEVREMNQASLFVRRS 410

  Fly   448 ----CSARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFVYV 508
                ...:|..|.|..|::::|:             |..|||.||.|||..|:.||..||  :|.
 Worm   411 LLPTSKRKTIEDRINRVEENRKN-------------AQKIDRYSRALFPLAFIIFNIFYW--IYY 460

  Fly   509 L 509
            |
 Worm   461 L 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	122/483 (25%)
lgc-57	NP_496306.2	LIC	44..460	CDD:455710	121/482 (25%)