Protein Alignment SecCl and lgc-52

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_502839.3
• Gene: lgc-52 / 190669
• WormBaseID: WBGene00013517
• Length: 423
• Species: Caenorhabditis elegans
• Alignment Length: 510
• Identity: 120/510 - (23%)
• Similarity: 211/510 - (41%)
• Gaps: 112/510 - (21%)

  Fly     6 LSEIFWITLILVLSIWTSVGVKAEEEECP--SMADAGSLQQTQLIQRLTHVCRYDRLERPFEYDS 68
            :..:|..|:::...|........|:..|.  .::.....:.|.|.:.|  :..|.|...|
 Worm     5 IQALFIETILMSARIHDVTYQHIEDFTCDDIGLSSLSGAKATDLARIL--MTNYSRNALP----- 62

  Fly    69 DGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKH-LSERL 132
              :..|:.|:..|.:..:.::::....|.:...:...:.|||||:...:.....|...| :..:|
 Worm    63 --EPAPVKVEVEITIQDISDISAITGTFTIDYWISAIWNDKRLAFSHLDPCRKNLSLDHDMEPKL 125

  Fly   133 WLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLES 197
            |.|::...|.:.:.:..:.:.::|..:.|.|.:.::.|:::...|.||.:.||.|...||.|.||
 Worm   126 WSPNVCIVNSKSTKVHDSPKPNILLMIFPNGTIWLNYRIRSEAPCQMNLRNFPLDSIRCSLVFES 190

  Fly   198 WMYNTSDLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAF-----AGNYSSL 257
            :.||.:|:.|:|...:|:|   .:| .:||:..|...         |:.:|:.     ||.:..|
 Worm   191 YSYNAADVELQWLEWSPVS---TVR-NDYNLPDFRMT---------NITYGSVTEAYTAGMWHRL 242

  Fly   258 SFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLP 322
            |.:::.:|..|||:|..|||:.:.|.|||::||:...|.|.||.|..|::::......:..|:||
 Worm   243 SVSIHFERLYGFYILQMYLPTYISVFISWIAFWMDTKALPARITLSVSSLMALTFQFGNIVKSLP 307

  Fly   323 KVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGG 387
            |.||:|..::|...|..|||.||:|.|.|             ..|.|
 Worm   308 KASYVKAIDIWMFSCVGFIFFSLIELAIV-------------AYNDK------------------ 341

  Fly   388 SLSNESRARS--CSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICSA 450
              .::.|.|.  | |:.|:  ::..:...|.|..:.|                      |.:.:.
 Worm   342 --MHDQRLREVRC-SVGNL--NSNGIGQYNSTTRRSF----------------------VELSAR 379

  Fly   451 RTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTF 505
            |...                      .|:...|||.:..|||.||..||.:||.:
 Worm   380 RAKG----------------------SELGASIDRVASMLFPTMFALFNLVYWAY 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	115/469 (25%)
		Neur_chan_LBD	44..267	CDD:280998	54/228 (24%)
		Neur_chan_memb	275..503	CDD:280999	55/229 (24%)
lgc-52	NP_502839.3	Neur_chan_LBD	45..248	CDD:280998	53/224 (24%)
		LIC	52..413	CDD:273305	113/463 (24%)
		Neur_chan_memb	259..>338	CDD:280999	32/91 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1260459at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820