Protein Alignment SecCl and lgc-40

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001407536.1
• Gene: lgc-40 / 188854
• WormBaseID: WBGene00020767
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 132/555 - (23%)
• Similarity: 245/555 - (44%)
• Gaps: 103/555 - (18%)

  Fly     2 MNLHLSEIFWITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQ-LIQRLTHVCRYDRLERPFE 65
            |.||....|.:::..:::::.|             ||...:..|: .:.:|.:...|:|...|.:
 Worm     1 MKLHTMIRFLLSVCCIVNVFES-------------ADLAFIPLTKAFLDKLKNETLYNRFATPTQ 52

  Fly    66 YDS----DGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQK 126
            ||.    .|..:|..|...:::..:.:.::..:.:.:....|..:.|.|||:   |.|..||.:.
 Worm    53 YDEYIRVHGTGVPTNVTLSMFIEGMSSFSAQTMDYHLDVYFQEEWYDHRLAH---NASAPILVRD 114

  Fly   127 -HLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQF 190
             .:.:.:|.|.::|||.|.::.....:.:.|..:.|.|.|....|:.....|.|:..|:|.|.|.
 Worm   115 LTVFKMMWHPDVYFANARSAAFQDITDDNFLVWVYPNGRVWYDARISIVSSCNMDLWKYPLDSQE 179

  Fly   191 CSTVLESWMYNTSDLILEW---EPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFA- 251
            |:..:.|:.|..:.|.|.|   |....|..:|::.:.:.::.   |..|       ...:|.:|
 Worm   180 CALRILSYAYPMTVLRLLWSEKEDVPAIDRNPDITMPDMSLK---HIRT-------GYCNGTYAT 234

  Fly   252 GNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSS 316
            |.:|.::....::||:..:::..|:|:.:||.|||.:|||:.|::|.|:.|..:|:|:..|.:::
 Worm   235 GEWSCMTAIFYVEREMMHHVMQTYVPTALIVVISWFNFWLEIDSAPARVSLSITTLLTISTQANA 299

  Fly   317 QSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSK--YIIKSTLTPR 379
            ....||:|||:|..:||...|..|:||.::||    ||....:|:|:.:.:.:  .|:.:.|:
 Worm   300 VKLALPEVSYMKAIDVWMGSCMAFVFGVMIEF----TICHYAKNLEMLRGDGQPSLIVDTALS-- 358

  Fly   380 PARRQIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADT 444
               ...|.:...:...|..::|    :..|.|| |:|..:...|   .::|..|.:|
 Worm   359 ---TLFGAARDIDDLVRKVATL----NEEEGVR-GDGEQHIALN---MLNPEEPRLR-------- 404

  Fly   445 VSICSARTNND-------HIVDVDKDKKDTPPTFTTMTPQEIAM--------------W------ 482
                |...|||       :.|..::.|:.......:...|::|.              |
 Worm   405 ----SLNQNNDVTANGTRYFVGAERMKRKRSKASLSRLRQQVASMRHATIDVSRRAFNWTRALRN 465

  Fly   483 ---------IDRRSRFLFPAMFLAFNALYWTFVYV 508
                     ||.|.|.:||.:||.||..||:|..|
 Worm   466 LRGRRVAQRIDERCRIVFPMIFLLFNVAYWSFYLV 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	123/509 (24%)
lgc-40	NP_001407536.1	LIC	31..498	CDD:455710	123/508 (24%)