Protein Alignment SecCl and lgc-50

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_498637.3
• Gene: lgc-50 / 188633
• WormBaseID: WBGene00020605
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 535
• Identity: 130/535 - (24%)
• Similarity: 217/535 - (40%)
• Gaps: 88/535 - (16%)

  Fly    10 FWITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYDSDGKRLP 74
            |.:.|.||...:::....:.::...:..:.|.|..|.|....||:..          :::|
 Worm     3 FLLVLQLVFFYFSAATTNSPKKCSRNSINLGKLIDTLLTDYDTHLLP----------EAEG---- 53

  Fly    75 IVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFN-RSDNILGQKHLSERLWLPHIF 138
            :.|...::|..:..::.....|.:..:....:||.||::|..| .:.||..:....:::|.|...
 Worm    54 VNVTIELHVQGVSGISEITGDFSLDVMYSEIWQDPRLSFKHLNVCATNITLKSDFRKKIWTPDTC 118

  Fly   139 FANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTS 203
            ..|.:.|||..:..::....|...|.|..:.|:.....|.:|.:.||||...|..||||:.:||.
 Worm   119 IINSKSSSIHSSPSENTFVILYENGLVWSNFRLNVKTPCSVNLKMFPFDSLSCEIVLESYSFNTD 183

  Fly   204 DLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKREIG 268
            ::.|.|. ..||:...::.|.::::.. |      .:|...|.:.....:.:.:.||  ..|..|
 Worm   184 EVRLMWH-DVPITMMEKVELPDFDLIG-W------STDHQRLEYPNGIWDRAKVKFT--FARRYG 238

  Fly   269 FYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEVW 333
            |||...|.|:.:.|..|||.|:....:...||.||.|::|:......:..::||:|||||..:||
 Worm   239 FYLFQSYFPTSLTVISSWVGFFFDVRSVSARITLGVSSLLALTFQFGNVLRHLPRVSYIKCLDVW 303

  Fly   334 FLGCTFFIFGSLVEFAFVNTI--WRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLSNESRAR 396
            .:....|||.:|||.|.|..:  |.|:..|. .||...::           .||..:...||:|.
 Worm   304 MIFSVIFIFCTLVELAIVCQLNRWERERQIG-SKVLGHWL-----------NQIRKTRKKESKAD 356

  Fly   397 SCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTE----CAEADTVSICSARTNNDHI 457
                           ..|.|.|.......:.|...|....|:    .|.|.|.:|....||.:.|
 Worm   357 ---------------EGGGGGVGGLLRKRIPVLAQLKAAATDSNSGAATAMTTAIQPPNTNLNSI 406

  Fly   458 VDVDKDKKDTPPTFTTMTPQEIAM-----------------------W------IDRRSRFLFPA 493
            .:.|..|. ....||::..:..|.                       |      :||.|..:||.
 Worm   407 TNSDNSKL-VANNFTSIEHETYAYEKKRGFSHCFQRFVYAICPPDRDWTITSVQVDRCSMIMFPL 470

  Fly   494 MFLAFNALYWTFVYV 508
            .||.||.:||:..::
 Worm   471 SFLIFNVVYWSIYFM 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	124/497 (25%)
		Neur_chan_LBD	44..267	CDD:280998	50/223 (22%)
		Neur_chan_memb	275..503	CDD:280999	68/262 (26%)
lgc-50	NP_498637.3	LIC	34..483	CDD:273305	125/500 (25%)
		Neur_chan_LBD	34..237	CDD:280998	51/226 (23%)
		Neur_chan_memb	245..480	CDD:280999	68/262 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810