Protein Alignment SecCl and lgc-54

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001343648.1
• Gene: lgc-54 / 188525
• WormBaseID: WBGene00020528
• Length: 493
• Species: Caenorhabditis elegans
• Alignment Length: 466
• Identity: 108/466 - (23%)
• Similarity: 203/466 - (43%)
• Gaps: 68/466 - (14%)

  Fly    60 LERPFEYDSDGKRLPI-----VVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAF-NR 118
            |.|.|:.:.:...:|:     ||.....:..:..::.....|.:..|....:.|.||.:... |.
 Worm    56 LRRLFDDNYNKNTVPLKTSATVVSVEFGIQNIAQVSEISASFTLDLLFSQIWHDPRLRFDHLTNC 120

  Fly   119 SDNILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQK 183
            ..|:.....:.|:||.|::.|.|.:::.|..:...::...:.|.|.|.::.|:|....|.::...
 Worm   121 LQNLTLGYSMVEKLWTPNVCFVNSKKTEIHSSPTPNIFLMIYPNGTVWVNYRLQVQSPCMVDLVL 185

  Fly   184 FPFDQQFCSTVLESWMYNTSDLILEWEPHTPISFDPEMRLTEYNMAQF-WHNTTIVQSDGDNLRH 247
            ||.|...|..::||:.||.:.:.|.|....|:....:.:|:::.:... |...:...:
 Worm   186 FPMDIMNCELIIESYAYNAAKVKLNWREWQPVFSIAKSKLSDFTLYGLQWTKNSFEYA------- 243

  Fly   248 GAFAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFIT 312
               ||.:..|:.::...|..|||:|..|:|:...|.:|:||||:...|.|.||.||.|::::...
 Worm   244 ---AGQWDQLTVSLTFSRAYGFYILQMYIPTYSSVFLSFVSFWIDLKALPARITLGVSSLMALTF 305

  Fly   313 LSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFV------NTIWRRKENIELKKVNSKYI 371
            ...:.:||||:|.|:|..:|:.:..|.|||.:::|.|||      |.:.|::...|.||  .:..
 Worm   306 QYGNVAKNLPRVGYVKSIDVYMVLTTAFIFLTMIEVAFVCYLDSENNLRRKERQAEKKK--ERVA 368

  Fly   372 IKSTLTPRPARRQIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVN-------QGFNNYLTVH 429
            :......|........:::|.:.|.|     ::.|:.:...:.|||.:       |..|.:.::|
 Worm   369 VLQRKKDRKKNNYGATTVTNANAAES-----DLRSNYDEPFSQNGTTSHKISISRQANNMFESLH 428

  Fly   430 PNLPIIRTECAEADTVSICSARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAM 494
                          .::.....|::|     |::.|.|            |..:|:..|..||..
 Worm   429 --------------ALAQFGLLTDDD-----DENTKWT------------AQNVDKFCRKAFPLS 462

  Fly   495 FLAFNALYWTF 505
            |...|.:||.:
 Worm   463 FCFLNLIYWCY 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	108/464 (23%)
		Neur_chan_LBD	44..267	CDD:280998	43/213 (20%)
		Neur_chan_memb	275..503	CDD:280999	59/240 (25%)
lgc-54	NP_001343648.1	Neur_chan_LBD	55..474	CDD:332142	108/466 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1260459at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820