Protein Alignment SecCl and exp-1

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_495229.3
• Gene: exp-1 / 186801
• WormBaseID: WBGene00001373
• Length: 539
• Species: Caenorhabditis elegans
• Alignment Length: 509
• Identity: 115/509 - (22%)
• Similarity: 203/509 - (39%)
• Gaps: 99/509 - (19%)

  Fly    19 SIWTSVGVKAEEEECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYDSDGKRLPIVVKTRIYV 83
            |:::|.||.:..|         :....|.::|:    :||..:.|    .:.|.....|:..:.|
 Worm    86 SVFSSGGVDSYGE---------TRDFLQFLRRI----QYDHRQVP----ENEKGEATYVEVSVVV 133

  Fly    84 YFLQNLNSDLLQFKMHALLQLRFQDKRLAY--KAFNRSDNILGQKHLSERLWLPHIFFAN----- 141
            ..::.::...:.:.:....:..::|.||.|  |.|.....:...:..:..||.|..|..|
 Worm   134 SNIRAVSEVTMDYALELFYRESWRDPRLQYDRKLFKNKTELALHESYTNFLWFPDTFVPNAIASK 198

  Fly   142 --ERES----SILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMY 200
              :|.|    |:|..||         .|.::.|.|:.....|.|:...||||:|.|...:||:.|
 Worm   199 NPQRNSISHRSLLRLDE---------TGKLLYSRRISLVCECTMDLTLFPFDKQLCKLGIESYGY 254

  Fly   201 NTSDLILEWEPHTPISFD-PEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLK 264
            ....::.:|......:.: .::||.::.:.:.:     |.|..::..    .||||.|.......
 Worm   255 TADHVVYKWSKGARTALELKKIRLPDFTIQEAY-----VTSQMESYA----TGNYSRLYVCFVFS 310

  Fly   265 REIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKV 329
            |..||..|...:||..:|..||||.|::.:.....::   |.:|:...|..|.::.:|:|||||.
 Worm   311 RSSGFCFLQLIIPSTAVVITSWVSLWMETETEFQDMI---SIILAITFLIFSYNEMMPRVSYIKA 372

  Fly   330 SEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLSNESR 394
            .:::...|...:|.||::.|.|            |.:..|.::.|         ..|.||...|:
 Worm   373 MDIYLGVCFMIVFLSLIKLALV------------KYMRQKIMLTS---------DSGNSLREMSQ 416

  Fly   395 ARSCSSLDNIVSSTESVRNGNG---TVNQGFNNYLTVHPNLPIIRTECAEADTVSICSARTNND- 455
            ..:...|....:|..:.||..|   .:|:.....|||    |....:.|..|     ....||:
 Worm   417 MSTRQRLRARKTSNMNFRNNGGGSIPINEEHQQMLTV----PNGEDKMANGD-----DKEANNNG 472

  Fly   456 --HIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFVY 507
              |:.|:.:.:       .|........||   |:.||...|:.| .|::..:|
 Worm   473 KSHLSDMLEIR-------ITQRTMHRFHWI---SQMLFFFGFVIF-CLFYFLIY 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	109/481 (23%)
		Neur_chan_LBD	44..267	CDD:280998	50/236 (21%)
		Neur_chan_memb	275..503	CDD:280999	56/233 (24%)
exp-1	NP_495229.3	LIC	103..515	CDD:273305	109/481 (23%)
		Neur_chan_LBD	111..311	CDD:280998	47/221 (21%)
		Neur_chan_memb	320..>397	CDD:280999	25/91 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810