Protein Alignment SecCl and acc-3

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_508810.2
• Gene: acc-3 / 186307
• WormBaseID: WBGene00018880
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 492
• Identity: 133/492 - (27%)
• Similarity: 222/492 - (45%)
• Gaps: 56/492 - (11%)

  Fly    30 EEECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSDLL 94
            ||.|.|        ...:|::|.:  .|.....|.|..       ::|...::|..:.::|....
 Worm    60 EELCTS--------DKTIIEKLLN--NYKSFRTPSESG-------VIVWIEVWVQEVNSVNEITS 107

  Fly    95 QFKMHALLQLRFQDKRLAYKAFNRSD-NILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTS 158
            .|.|...:...:.|..|.|:..|... |:.....:.:::|.|:..|.|.:.::|..:..|:|...
 Worm   108 DFDMDIYVTELWMDSALRYEHLNPCKYNLSLNSEILDQIWKPNTVFINSKSANIHKSPFKNVFLM 172

  Fly   159 LSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTSDLILEW-EPHTPIS-FDPEM 221
            :.|.|.|.::.|:|....|.|:|..||.|||.|...|||:.||..::.::| ...||:| ...|:
 Worm   173 IYPNGTVWVNYRVQVKGPCSMDFSAFPMDQQSCHLTLESFSYNNQEVDMQWMNWTTPLSLLKKEI 237

  Fly   222 RLTEYNMAQFWHNTTIVQSDGDNLRHGAF-AGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAIS 285
            .|.::.|:.:          ..:|:|..: ||.::.|:.|....|..|:|:...|:|:.:.:.||
 Worm   238 VLPDFVMSNY----------STSLKHEIYPAGVWNELTMTFVFSRRYGWYIFQAYIPTYLTIFIS 292

  Fly   286 WVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAF 350
            |:||.|.....|.|.|||.:::|:......:..:|||:|||:|..:||.|.|..|:|.||:|.|.
 Worm   293 WISFCLGPKMIPARTMLGVNSLLALTFQFGNIMRNLPRVSYVKALDVWMLVCLTFVFCSLLELAI 357

  Fly   351 VNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLSNESRARSCSSLDNIVSSTESVRNG- 414
            :.::..|.||.:.::...:       .....:.|.|...|..|...|.||..|   |....||.
 Worm   358 IGSMGARSENRQAQQQKQQ-------DEEATKHQKGRENSTCSHLMSPSSCPN---SPRICRNHI 412

  Fly   415 NGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICSARTNNDHIVDVD----KDKKDTPPTFTTMT 475
            ...|.|.|.:|.:..|.:. .|...|.:.|:|.......::.::.:|    .........|::|.
 Worm   413 PNDVPQSFKSYGSTDPRMR-KRLIIASSSTISHAPNANRSEKVLLLDGLEETQFSQVETKFSSMA 476

  Fly   476 PQEIAM---W----IDRRSRFLFPAMFLAFNALYWTF 505
              .|.|   |    |||.|..:||.:|..||.:|||:
 Worm   477 --SIKMKKHWTTEEIDRLSMIMFPGLFTLFNIIYWTY 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	128/477 (27%)
		Neur_chan_LBD	44..267	CDD:280998	55/226 (24%)
		Neur_chan_memb	275..503	CDD:280999	69/239 (29%)
acc-3	NP_508810.2	Neur_chan_LBD	69..512	CDD:332142	129/475 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810