Protein Alignment SecCl and lgc-39

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_504821.3
• Gene: lgc-39 / 184265
• WormBaseID: WBGene00017314
• Length: 563
• Species: Caenorhabditis elegans
• Alignment Length: 520
• Identity: 132/520 - (25%)
• Similarity: 226/520 - (43%)
• Gaps: 120/520 - (23%)

  Fly    35 SMADAGSLQQTQLIQRLTHVC-------RYDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSD 92
            |....|.|:.::...||..|.       .|:....|.:  |.|||..:.|  .:|:..:.:..:.
 Worm   105 SGGQTGELKWSESGDRLLKVIGNGVVEDGYNMFMAPGQ--SQGKRTDVHV--AVYIESMSSFKAQ 165

  Fly    93 LLQFKMHALLQLRFQDKRLAYKAFNRSDNIL-GQKHLSERLWLPHIFFANERESSILGTDEKDVL 156
            .:.|::...|.:.:.|:|||:   |.:..|| ..|.:::|:|.|.::|.|.:.:.:......:::
 Worm   166 SMDFEVDMYLAMGWFDRRLAH---NCTHPILVTSKLIADRIWYPDLYFVNSKYAYLQEVTTPNLM 227

  Fly   157 TSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTSDLILEWE---PHTPISFD 218
            ..:.|:|.:..:.|:..:|.|.|:.:.||.|.|.|...::|:.|....:.|.|.   |:.||.|:
 Worm   228 VIVYPDGLIFKTMRLDVTLSCMMDLKLFPLDYQECPLTIQSFAYIEQIVNLTWRDDPPNFPIGFN 292

  Fly   219 PEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGN--YSSLSFTVNLKREIGFYLLDYYLPSMMI 281
            |:::|.:..:.    |...|:..|.   :..|.|.  :|.:...:.:||.:.|:::..|:|:.|:
 Worm   293 PDIKLNDMQIT----NKRFVKCAGP---YPMFRGEAAWSCIQGYIVMKRLVLFHIIQTYIPTGML 350

  Fly   282 VAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLV 346
            |:|||:||||...|||.||.|..:::|:..|:|:...::||:|||||..::|.......||..|:
 Worm   351 VSISWMSFWLDPRASPARISLTITSLLTLTTMSNGARQDLPQVSYIKALDIWLTFSQALIFLVLL 415

  Fly   347 EFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLSNESRARSCSSLDNIVSSTESV 411
            |::||                |.|:.|.| |....|     ::..|.|.:.|       ...|..
 Worm   416 EYSFV----------------SYYMTKRT-TDCSHR-----NMFYEERVQEC-------KREEKA 451

  Fly   412 RNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICSARTNNDHIVDVDKDKKD---------- 466
            |..            .|:.|.|:|                .||....|::::||.
 Worm   452 RKS------------IVNNNKPVI----------------ANNTEGSDLNRNKKSQQFSLTHGIS 488

  Fly   467 ------------TP-PT-----FTTMTP--------QEIAMWIDRRSRFLFPAMFLAFNALYWTF 505
                        || |:     |.|..|        :.||..||..||:|||.:|..|...||.:
 Worm   489 ACLNESSALMSVTPVPSRLFTKFDTNKPCARCSEKNERIAFKIDEYSRWLFPTVFSLFCVSYWLY 553

  Fly   506  505
             Worm   554  553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	129/510 (25%)
		Neur_chan_LBD	44..267	CDD:280998	55/235 (23%)
		Neur_chan_memb	275..503	CDD:280999	71/263 (27%)
lgc-39	NP_504821.3	LIC	119..554	CDD:273305	129/506 (25%)
		Neur_chan_LBD	132..336	CDD:280998	52/217 (24%)
		Neur_chan_memb	343..551	CDD:280999	71/264 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910