Protein Alignment SecCl and glc-4

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_495489.2
• Gene: glc-4 / 182971
• WormBaseID: WBGene00001594
• Length: 500
• Species: Caenorhabditis elegans
• Alignment Length: 561
• Identity: 134/561 - (23%)
• Similarity: 221/561 - (39%)
• Gaps: 137/561 - (24%)

  Fly    11 WITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRLTHVC----RYDRLERPFEYDSDGK 71
            :::::|.|.: :|...|::.:.|...|.:......|..:....||    .||...||     .|:
 Worm     6 YVSVLLALLV-SSTAKKSKTKSCKRTAFSRHTTNYQAWREQMTVCDLLQDYDAAVRP-----SGR 64

  Fly    72 ------RLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQ----DKRLAYKAFNRSDNILGQK 126
                  |..::|.|.:.:..:..::...::|    :.|.||:    |.||   .|.....:|...
 Worm    65 TPYNDTRGAVMVTTSLNIRSISAVSEKNMEF----VAQFRFRQEWYDDRL---RFIEHQGLLSSD 122

  Fly   127 HLS---------ERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQ 182
            :.:         :.||:|..||.||:.......::::....:..:|.:|...|:...|.|.|:..
 Worm   123 YRNFEFIHVARDQSLWIPDTFFQNEKNGWYHMLNQENRFLKIRSDGKLIYDRRLTLHLACSMHLS 187

  Fly   183 KFPFDQQFCSTVLESWMYNTSDLILEWE-PHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLR 246
            ::|.|.|.|.....|:.|.|:|:...|: |...|.......|..:.:|.|.:.:...:::
 Worm   188 RYPMDHQNCEIAFASYAYTTADIEYIWDVPAIQIHEGANGALPNFEIASFKNASCTSKTN----- 247

  Fly   247 HGAFAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFI 311
                .|.||.|...:.|.|...|:||..|:||.|:|.::|||:|:...::..|:.|...|:|:.|
 Worm   248 ----TGTYSCLKVEIRLNRVFSFFLLQLYIPSSMLVGVAWVSYWIDWKSTAARVPLAIVTLLTMI 308

  Fly   312 TLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTL 376
            |.|.:.:.|||.|||.|..::|...|..|||.||:|:|.||.:....|:.::||
 Worm   309 TTSHAINSNLPPVSYAKSIDIWVGACVVFIFFSLIEYAVVNYVGILDEHRQMKK----------- 362

  Fly   377 TPRPARRQIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHP--------NLP 433
                       :..|.||..:....||...|.:|               ||..|        ..|
 Worm   363 -----------AACNRSRLSNVIENDNFGESLQS---------------LTFSPQEKKRLIRRRP 401

  Fly   434 IIRTECAEADTVSICSARTNNDHIVDVDKDKKDTPP----------TFTTMTP---------QEI 479
            ....|..|.|..:|        .:||      ..||          ||...|.         .|:
 Worm   402 KKNMEMQEGDFEAI--------EMVD------RGPPRSAGLMEEGWTFHDTTDLVYIGQRKRVEL 452

  Fly   480 AMW------------IDRRSRFLFPAMFLAFNALYWTFVYV 508
            ..|            ||..:|.:||..|:.||..||: :|:
 Worm   453 VRWCSVLSSRGRAERIDIIARIIFPLAFILFNFAYWS-IYL 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	127/524 (24%)
		Neur_chan_LBD	44..267	CDD:280998	53/246 (22%)
		Neur_chan_memb	275..503	CDD:280999	69/266 (26%)
glc-4	NP_495489.2	LIC	26..491	CDD:273305	129/537 (24%)
		Neur_chan_LBD	50..258	CDD:280998	48/228 (21%)
		Neur_chan_memb	271..488	CDD:280999	69/267 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910