Protein Alignment SecCl and lgc-55

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_507870.2
• Gene: lgc-55 / 180312
• WormBaseID: WBGene00013746
• Length: 538
• Species: Caenorhabditis elegans
• Alignment Length: 513
• Identity: 132/513 - (25%)
• Similarity: 232/513 - (45%)
• Gaps: 78/513 - (15%)

  Fly    24 VGVKAEEEECPSMADAGSLQQ--TQLIQRLTHVCRYDRLERPFEYDSDGKRLPIVVKTRIYVYFL 86
            :|:..:.||.......|..::  |:::..|  :.:|||...|       |...:.|...:.:..:
 Worm    66 LGLSQDSEEDEPFCVLGQAEKAATRILTEL--LSKYDRNLVP-------KMKGVDVDVELLIQRV 121

  Fly    87 QNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSER----LWLPHIFFANERESSI 147
            ..::.......||.|....:.|..|::: .....:.|....||.|    :|||::...|.:.|:|
 Worm   122 SEISEIQSSSTMHILFSQIWHDPGLSFE-HEEGAHCLTNLSLSHRMVDNIWLPNVCIVNSKGSAI 185

  Fly   148 LGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTSDLILEWEPH 212
            ..:...::..::.|.|.|.::.|:.....|.|:|..||.|:..|:|:.||:.:|...:.|.|:..
 Worm   186 HKSPTPNIFLAIFPNGTVWMNYRVVVESPCEMDFSFFPMDRVMCTTIFESYAFNVGKVRLHWKRQ 250

  Fly   213 -TPISFDPEMRLTEYNMAQFWH-NTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKREIGFYLLDYY 275
             .|:.|..:::|.:::|.:|.| ..|.:..          ||.:..|:..:..:|..|||:|..|
 Worm   251 GQPVEFIDDVKLPDFHMTKFVHEKATFIYP----------AGVWDQLNIKLLFRRSYGFYILQIY 305

  Fly   276 LPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFF 340
            ||:..:|.|||:||||...:.|.|:.||.|::::.....|:.|::||||||:|..:::..||..:
 Worm   306 LPTYCMVLISWISFWLDRRSLPARVTLGVSSLMALTLQYSNVSRSLPKVSYVKGLDLFMFGCIVY 370

  Fly   341 IFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLSNESRARSCSSLDNIV 405
            ||.|:||.|.|.::.:||:    ::.|:.                |..||::...:      ||.
 Worm   371 IFLSIVELAVVGSLEQRKQ----QRTNAD----------------GDFLSDDDIKK------NIF 409

  Fly   406 S---STESVRNGNGTVNQGFNNYLTVHP--NLPIIRTECAEADTVSIC-------SAR------- 451
            .   ||:|.::|.|..:..|:...:...  ..|..|||.||...|. |       |.|
 Worm   410 QRTFSTKSFKSGYGARHHQFSECASPEDGGEWPKTRTEWAERTYVE-CPEPEPPESNRHPEVEND 473

  Fly   452 TNNDHIVDVDKDKKDTPPTFTTMTPQEIAMW----IDRRSRFLFPAMFLAFNALYWTF 505
            :||..:|.|.:.:.........|:.:....|    :||..:.|||..|...|.:||.:
 Worm   474 SNNKMLVLVRQRRASRKRRKRLMSGKLFQRWTAEDMDRFCQKLFPITFTFCNLIYWMY 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	128/492 (26%)
		Neur_chan_LBD	44..267	CDD:280998	51/230 (22%)
		Neur_chan_memb	275..503	CDD:280999	71/250 (28%)
lgc-55	NP_507870.2	Neur_chan_LBD	88..295	CDD:280998	50/226 (22%)
		LIC	90..532	CDD:273305	127/489 (26%)
		Neur_chan_memb	304..>391	CDD:280999	36/90 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810