Protein Alignment SecCl and glc-3

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_504441.1
• Gene: glc-3 / 178930
• WormBaseID: WBGene00001593
• Length: 484
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 150/545 - (27%)
• Similarity: 233/545 - (42%)
• Gaps: 130/545 - (23%)

  Fly    12 ITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYDSDGKRLPI- 75
            :.::|:::.|...|      .|.:.:|      |::|::|... .||...||     .|..|.|
 Worm     7 LNILLIVAFWIVGG------NCDASSD------TEIIKKLLGK-GYDWRVRP-----PGINLTIP 53

  Fly    76 -----VVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQ----DKRLAY--KAFNRSDNIL---GQK 126
                 |:   :||..|....|.:....|...:||.|:    |.||||  ...:..|.::   ||
 Worm    54 GTHGAVI---VYVNMLIRSISKIDDVNMEYSVQLTFREEWVDGRLAYGFPGDSTPDFLILTAGQ- 114

  Fly   127 HLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFC 191
                ::|:|..||.||:::.....|:.:||..:..:|.::.|.|:...|.|.|:.|.:|.|.|.|
 Worm   115 ----QIWMPDSFFQNEKQAHKHDIDKPNVLIRIHRDGRILYSVRISMVLSCPMHLQYYPMDVQTC 175

  Fly   192 STVLESWMYNTSDLILEWEPHTPISFD-------PEMRLTEYNMAQFWHNTTIVQSDGDNLRHGA 249
            ...|.|:.|..:|:...|:...|:...       |...|...       :||:..|..:
 Worm   176 LIDLASYAYTENDIEYRWKKTDPVQLKKGLHSSLPSFELNNV-------DTTLCTSKTN------ 227

  Fly   250 FAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLS 314
             .|.||.|...:.|:|:..:|||..|:||.|:|.:|||||||...|.|.|:.||.:|:|:..|.:
 Worm   228 -TGTYSCLRTVLELRRQFSYYLLQLYIPSTMLVIVSWVSFWLDRGAVPARVTLGVTTLLTMTTQA 291

  Fly   315 SSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTI-----WRRKEN--------IELKKV 366
            |..:..||.|||.|..:||...|..||||:|:|||:|..|     ::|.:|        ||.|:.
 Worm   292 SGINAKLPPVSYTKAIDVWIGACLTFIFGALLEFAWVTYISSRSFYKRNKNCSSRNSLLIETKQA 356

  Fly   367 NSKYIIKSTLTPR----PARRQIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLT 427
               .||.:|:..:    |...::|.:.:.:...|               ::|||......|.::.
 Worm   357 ---LIIPNTVVAQFPEHPEEVEMGLAQAPDVWIR---------------QSGNGKTVSRVNGHIN 403

  Fly   428 VHPNLPIIRTECAEADTVSICSARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRR------ 486
             |.|        .||..:.|..|:..|...|           .:|......:..||..|
 Worm   404 -HNN--------DEAAELIIFDAKHKNRRFV-----------WWTNFRNIRLIRWIRNRLNVDDN 448

  Fly   487 -------SRFLFPAMFLAFNALYWT 504
                   ||.|||.:|:.||.:|||
 Worm   449 AKRADLISRVLFPTLFVCFNFVYWT 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	145/514 (28%)
glc-3	NP_504441.1	LIC	29..475	CDD:455710	144/511 (28%)