Protein Alignment SecCl and lgc-37

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_499662.2
• Gene: lgc-37 / 176694
• WormBaseID: WBGene00013914
• Length: 483
• Species: Caenorhabditis elegans
• Alignment Length: 474
• Identity: 115/474 - (24%)
• Similarity: 202/474 - (42%)
• Gaps: 84/474 - (17%)

  Fly    52 THVCRYDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAF 116
            |.:...|:..||...|:.    |:.|:..|.:..:..::...::|.:....:.::.|:|||:...
 Worm    50 TILLNQDKNFRPVNPDNS----PLQVEVDISIRSMGPVSEQNMEFSLDCYFRQKWLDRRLAFTPI 110

  Fly   117 NRS--DNILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWM 179
            |.|  :..|..|.|.: :|:|..:..|.|:|.:......::|..:..:|.|.:|.|:.....|.|
 Worm   111 NPSKPEIPLASKMLKD-IWIPDTYIRNGRKSYLHTLTVPNILFRVRSDGQVHVSQRLTIRSRCQM 174

  Fly   180 NFQKFPFDQQFCSTVLESWMYNTSDLILEWEPHTPISFDPEM--RLTEYNMAQFWHNTTIVQSDG 242
            ..:|||.|.|.|...:.|..|.:.|::.:|:   .:..|.:|  .|::|.:..       :....
 Worm   175 FLKKFPMDTQACPIEVGSLGYFSKDVVYKWK---DVELDAKMGNTLSQYQVLS-------LSKSE 229

  Fly   243 DNLRHGAFAG-NYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTST 306
            .|:....|:. |.|.|:....|:|:.|:|:|..|.|..::|.:||||||:..:|||.|:.||..|
 Worm   230 RNVSDFRFSDRNISVLNVYFKLQRQQGYYILQIYTPCTLVVVMSWVSFWINKEASPARVSLGIMT 294

  Fly   307 MLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVN---TIWRRKENIELKKVNS 368
            :||..|:......:|||||:....:|:.|.|..|:|.::||:|.:|   .::.||:..:||.:..
 Worm   295 VLSMSTIGFGLRTDLPKVSHSTALDVYILTCFVFLFAAMVEYAVINYAQIVYIRKQIHDLKGLEQ 359

  Fly   369 KYIIKSTLTPRPARRQIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLP 433
            ...:....|        .|.:.  :|.|....:|::....|..|                ...:|
 Worm   360 NTAMGQMFT--------AGLMG--ARRRDTIQVDDLTVEKEEAR----------------LKAVP 398

  Fly   434 IIRTECAEADTVSICSARTNNDHIVDVDKDKKDTPPTFTTMT--------------PQEIAMWID 484
            ..:..|.                     ||::.....|..|.              |.|:...||
 Worm   399 WWKKLCF---------------------KDEQGNTSMFYRMAVKAAIAKKTLRNGDPAEVVNKID 442

  Fly   485 RRSRFLFPAMFLAFNALYW 503
            ..|:..||.:::.||..||
 Worm   443 NFSKLAFPTLYIIFNVFYW 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	115/474 (24%)
		Neur_chan_LBD	44..267	CDD:280998	51/219 (23%)
		Neur_chan_memb	275..503	CDD:280999	59/244 (24%)
lgc-37	NP_499662.2	LIC	44..464	CDD:273305	115/474 (24%)
		Neur_chan_LBD	45..254	CDD:280998	50/218 (23%)
		Neur_chan_memb	262..461	CDD:280999	59/245 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810