Protein Alignment SecCl and lgc-46

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_497338.2
• Gene: lgc-46 / 175279
• WormBaseID: WBGene00022106
• Length: 508
• Species: Caenorhabditis elegans
• Alignment Length: 509
• Identity: 127/509 - (24%)
• Similarity: 207/509 - (40%)
• Gaps: 90/509 - (17%)

  Fly    48 IQRLTHVCRYDRLERPFEYDSDGKRLPIV------------------------------------ 76
            ::|||.  .||     :|.|..|...||:
 Worm    30 LRRLTR--NYD-----WEVDEHGGLKPIINPAKVERATKNCANDSFILGTIMSNYNRHKIPGGQV 87

  Fly    77 -VKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSD-NILGQKHLSERLWLPHIFF 139
             |:..::|..:..::.....|::...:...:.|..|.|...|... |:.....|.|:||.|:..|
 Worm    88 DVEVEVWVQEITTISDITSDFQLDIYIYETWYDPALNYAFMNPCKYNLSLNSVLLEKLWTPNSCF 152

  Fly   140 ANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTSD 204
            .|.:.:.|..:...::...:...|.|..:.|::....|.|:..|||||...||...||:.|||.:
 Worm   153 INSKTADIHKSPFPNIFLMIYANGTVWTNYRLKLQGPCIMDLTKFPFDNVTCSLTFESFNYNTDE 217

  Fly   205 LILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKREIGF 269
            :.::|..:.......:|.|.:|.:.......|..:..         ||.:..|:.:...||..|:
 Worm   218 VKMDWSVNGVQKMRDKMELADYELVDIHKIRTTEEYP---------AGYWHELTMSFEFKRRAGW 273

  Fly   270 YLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEVWF 334
            |:|..|||:.:.:.|||:||.|.:.|.|.|.|||.:::|:......:..:|||:|||:|..:||.
 Worm   274 YILQAYLPTYLTICISWISFALGSKAIPARTMLGVNSLLAMTFQFGNIIRNLPRVSYVKAIDVWM 338

  Fly   335 LGCTFFIFGSLVEFAFVNTIWRRKENIELKKVN-SKYIIKSTLTPRPARRQIGGSL--------S 390
            |.|..|:|.||:|.|:|..:.|.:|....|.:. |..:......|.|.::....|.        .
 Worm   339 LSCMTFVFCSLLELAWVGYLSREEEPTSAKCLQPSAQVAPKPCHPPPVQQNANNSSVHRRQKQPK 403

  Fly   391 NESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICSARTNND 455
            ||..:...|..||...........||.|.....::                   .|.||....|
 Worm   404 NEEESALLSLRDNDYGYIPPGFGLNGNVANAMKSF-------------------SSSCSCEPTN- 448

  Fly   456 HIVDVDKDKKDTPPTFTTMT------PQEIAMWIDRRSRFLFPAMFLAFNALYW 503
             :|::..|:.:|.||.|:.:      .:.:|..||..|.|:||.:|:.||..||
 Worm   449 -VVNLMLDEAETIPTSTSSSLSRKQRREILAHKIDSVSVFMFPFLFVLFNIAYW 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	127/509 (25%)
		Neur_chan_LBD	44..267	CDD:280998	53/256 (21%)
		Neur_chan_memb	275..503	CDD:280999	69/242 (29%)
lgc-46	NP_497338.2	Neur_chan_LBD	73..504	CDD:332142	117/459 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810