Protein Alignment SecCl and lgc-34

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_493752.1
• Gene: lgc-34 / 173443
• WormBaseID: WBGene00020836
• Length: 390
• Species: Caenorhabditis elegans
• Alignment Length: 513
• Identity: 114/513 - (22%)
• Similarity: 185/513 - (36%)
• Gaps: 145/513 - (28%)

  Fly    12 ITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYD-SDGKRLPI 75
            |.|.|||   .|:||.:.::...|.. .|:  :.|::.|:  :..||...||...| :|..  .|
 Worm     4 IFLFLVL---LSIGVCSAQKAFHSRR-LGT--EGQIVGRI--LSEYDSSSRPPVRDHADNS--AI 58

  Fly    76 VVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRS--DNIL--GQKHLSERLWLPH 136
            :|.|.|::..|...|:   ..::...|:.::||.||.|....|.  |.|.  |.:    ::|.|.
 Worm    59 LVITNIFINRLIWHNN---YAEVDLYLRQQWQDSRLKYDVDTREGIDEIRLPGNR----KIWEPD 116

  Fly   137 IFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASL-YCWMNFQKFPFDQQFCSTVLESWMY 200
            .:|.:.:|.|....:.|.::  :.|.|.:..|.|:...| |.:.....|...:|| :..|.|:.|
 Worm   117 TYFTSGKELSRNEKNSKHIV--VEPSGYIRSSERVLLELPYAYGTMFPFTNSRQF-TIKLGSYNY 178

  Fly   201 NTSDLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSD---GDNLRHGAFAGN--------- 253
            :..|::..|....|:.                 |...|..|   ||.....|.||:
 Worm   179 DIDDIVYLWANSPPLV-----------------NPIEVSQDLLKGDLTFEEASAGDCVGNYTVGV 226

  Fly   254 YSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQS 318
            ||.:...|.........|:.::|||:.::..||:.||:....|.||.:   |..:.|..|::...
 Worm   227 YSCIDAHVYFSASTISGLMSWFLPSLFLLIGSWLHFWIHGSWSVPRTI---SAAVPFFILAAYYI 288

  Fly   319 KNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARR 383
             .:.:.||.:....|...|....|.|.||:..|.....|: :|..|          ||.|:.
 Worm   289 -FMREDSYTQAQGAWLAFCLVLTFFSFVEYFLVICCGGRR-SIRYK----------TLGPQE--- 338

  Fly   384 QIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSIC 448
                              |:.:.:.:.      ||...:|.             .||
 Worm   339 ------------------DHPMGAAKE------TVEVAYNE-------------GCA-------- 358

  Fly   449 SARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFV 506
            |.|.||.                           ||..||..||.:.:.|..:|:.|:
 Worm   359 SFRDNNG---------------------------IDVISRVAFPIVTIVFLIIYFIFI 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	103/479 (22%)
		Neur_chan_LBD	44..267	CDD:280998	56/240 (23%)
		Neur_chan_memb	275..503	CDD:280999	45/227 (20%)
lgc-34	NP_493752.1	LIC	1..388	CDD:273305	113/510 (22%)
		LGIC_ECD_anion	58..237	CDD:349788	48/205 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910