Protein Alignment SecCl and glc-2

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_491470.1
• Gene: glc-2 / 172103
• WormBaseID: WBGene00001592
• Length: 434
• Species: Caenorhabditis elegans
• Alignment Length: 502
• Identity: 120/502 - (23%)
• Similarity: 214/502 - (42%)
• Gaps: 92/502 - (18%)

  Fly    12 ITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYDSDGKRLPIV 76
            :.|:|::.:.|:.....:.|:             :::..|  :..||...||...:|..:. .:.
 Worm    10 LLLLLLMPVVTNGEYSMQSEQ-------------EILNAL--LKNYDMRVRPPPANSSTEG-AVN 58

  Fly    77 VKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYK--AFNRSDNILGQKHLSERLWLPHIFF 139
            |:..|.:..|..::...:::.:....:.::.|.||||:  .|......|...|:.:.||:|..||
 Worm    59 VRVNIMIRMLSKIDVVNMEYSIQLTFREQWIDPRLAYENLGFYNPPAFLTVPHVKKSLWIPDTFF 123

  Fly   140 ANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTSD 204
            ..|:.:.....|.:::...:.|:|.::.|:|:..:..|.|..|.:|.|.|.|:..|.|:.:..:|
 Worm   124 PTEKAAHRHLIDMENMFLRIYPDGKILYSSRISLTSSCPMRLQLYPLDYQSCNFDLVSYAHTMND 188

  Fly   205 LILEWEPHTPISFDPEM--RLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKREI 267
            ::.||:|.||:...|.:  .|..:.:..:..|       .|...| ...|:|..|...:..||:.
 Worm   189 IMYEWDPSTPVQLKPGVGSDLPNFILKNYTTN-------ADCTSH-TNTGSYGCLRMQLLFKRQF 245

  Fly   268 GFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEV 332
            .:||:..|.|:.|||.:||||||:...::..|:.||.:|:|:..|:.|:.:..||.|||:||.:|
 Worm   246 SYYLVQLYAPTTMIVIVSWVSFWIDLHSTAGRVALGVTTLLTMTTMQSAINAKLPPVSYVKVVDV 310

  Fly   333 WFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLSNESRARS 397
            |...|..|:||:|:|:||
 Worm   311 WLGACQTFVFGALLEYAF----------------------------------------------- 328

  Fly   398 CSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICSARTNNDHIVDVDK 462
                   ||..:|||..:.:..:...........|.::..|..:..    |:..|........||
 Worm   329 -------VSYQDSVRQNDRSREKAARKAQRRREKLEMVDAEVYQPP----CTCHTFEARETFRDK 382

  Fly   463 DKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFVYVL 509
            .::    .||  .|..:...||..:||:.|..|||||.:||....::
 Worm   383 VRR----YFT--KPDYLPAKIDFYARFVVPLAFLAFNVIYWVSCLIM 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	116/465 (25%)
glc-2	NP_491470.1	LIC	29..419	CDD:455710	117/477 (25%)