Protein Alignment SecCl and Glra4

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_034427.2
• Gene: Glra4 / 14657
• MGIID: 95750
• Length: 456
• Species: Mus musculus
• Alignment Length: 523
• Identity: 144/523 - (27%)
• Similarity: 248/523 - (47%)
• Gaps: 104/523 - (19%)

  Fly    13 TLI---LVLSIWTSVG------VKAEEEECPSMADAGSLQQTQLIQRLT-HVCRYDRLERPFEYD 67
            ||:   |.|.:||..|      ..|:|:....:..:..:..:..:.:|. ....||...||
Mouse     3 TLVPASLFLLLWTLPGKVLLSVALAKEDVKSGLKGSQPMSPSDFLDKLMGRTSGYDARIRP---- 63

  Fly    68 SDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSERL 132
             :.|..|:.|...|::....::....:.::::..|:.::.|.||||:.: ..|::.....:.:.:
Mouse    64 -NFKGPPVNVTCNIFINSFGSVTETTMDYRVNVFLRQQWNDPRLAYREY-PDDSLDLDPSMLDSI 126

  Fly   133 WLPHIFFANERESSI--LGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVL 195
            |.|.:|||||:.::.  :.||.|  |..:...|||:.|.|:...|.|.|:.:.||.|.|.|:..|
Mouse   127 WKPDLFFANEKGANFHEVTTDNK--LLRIFKNGNVLYSIRLTLILSCPMDLKNFPMDIQTCTMQL 189

  Fly   196 ESWMYNTSDLILEWEPHTPISFDPEMRLTE-YNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSF 259
            ||:.|..:||:.||     :...|.:::.| ..:.||     |::.:.|   .|....:|::..|
Mouse   190 ESFGYTMNDLMFEW-----LEDAPAVQVAEGLTLPQF-----ILRDEKD---LGYCTKHYNTGKF 241

  Fly   260 T-----VNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSK 319
            |     .:|:|::|:||:..|:||::||.:||||||:..||:|.|:.||.:|:|:..|.||....
Mouse   242 TCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRA 306

  Fly   320 NLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRR-KENIELKKVNSKYIIKSTLTPRPARR 383
            :||||||:|..::|...|..|:|.:|:|:|.||.:.|: ||.:.|::             |..|:
Mouse   307 SLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFMRLRR-------------RQRRQ 358

  Fly   384 QIGGSLSNESR-------ARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAE 441
            ::...:..|||       ...|            ::..:|...:|.:.| :..|..|:::    |
Mouse   359 RMEEDIIRESRFYFRGYGLGHC------------LQARDGGPMEGSSIY-SPQPPTPLLK----E 406

  Fly   442 ADTVSICSARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFV 506
            .:|:          ..:.||:.|:                 ||..||.:||..||.||..||...
Mouse   407 GETM----------RKLYVDRAKR-----------------IDTISRAVFPFTFLVFNIFYWVVY 444

  Fly   507 YVL 509
            .||
Mouse   445 KVL 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	133/478 (28%)
Glra4	NP_034427.2	LIC	9..444	CDD:273305	140/512 (27%)