Protein Alignment SecCl and Glra1

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001277750.1
• Gene: Glra1 / 14654
• MGIID: 95747
• Length: 457
• Species: Mus musculus
• Alignment Length: 507
• Identity: 143/507 - (28%)
• Similarity: 238/507 - (46%)
• Gaps: 89/507 - (17%)

  Fly    11 WITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYDSDGKRLPI 75
            |.|::. .|:..|...:|.......|:.:..|.  :|:.|.:   .||...||     :.|..|:
Mouse    12 WETIVF-FSLAASKEAEAARSAPKPMSPSDFLD--KLMGRTS---GYDARIRP-----NFKGPPV 65

  Fly    76 VVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSERLWLPHIFFA 140
            .|...|::....::....:.::::..|:.::.|.||||..: ..|::.....:.:.:|.|.:|||
Mouse    66 NVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEY-PDDSLDLDPSMLDSIWKPDLFFA 129

  Fly   141 NERESSI--LGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTS 203
            ||:.:..  :.||.|  |..:|..|||:.|.|:..:|.|.|:.:.||.|.|.|...|||:.|..:
Mouse   130 NEKGAHFHEITTDNK--LLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMN 192

  Fly   204 DLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGA---FAGNYSSLSFTVNLKR 265
            |||.||:....:.....:.|.::          |::.:.| ||:..   ..|.::.:....:|:|
Mouse   193 DLIFEWQEQGAVQVADGLTLPQF----------ILKEEKD-LRYCTKHYNTGKFTCIEARFHLER 246

  Fly   266 EIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVS 330
            ::|:||:..|:||::||.:||:|||:..||:|.|:.||.:|:|:..|.||....:||||||:|..
Mouse   247 QMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAI 311

  Fly   331 EVWFLGCTFFIFGSLVEFAFVNTIWRR-KENIELKKVNSKYIIKSTLTPRPARRQIGGSLSNESR 394
            ::|...|..|:|.:|:|:|.||.:.|: ||.:..::                           .|
Mouse   312 DIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRR---------------------------KR 349

  Fly   395 ARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEA-DTVSICSARTNNDHIV 458
            ....|.:.|:....|   .|.|..|  |:.| .:.|       .|.:| |.:|:..|..||
Mouse   350 RHHKSPMLNLFQDDE---GGEGRFN--FSAY-GMGP-------ACLQAKDGISVKGANNNN---- 397

  Fly   459 DVDKDKKDTPPTFTTMTPQEI-------AMWIDRRSRFLFPAMFLAFNALYW 503
                  ...||...:.:|:|:       |..||:.||..||..||.||..||
Mouse   398 ------TTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYW 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	136/475 (29%)
		Neur_chan_LBD	44..267	CDD:280998	59/227 (26%)
		Neur_chan_memb	275..503	CDD:280999	72/236 (31%)
Glra1	NP_001277750.1	LIC	7..446	CDD:273305	143/507 (28%)
		Strychnine-binding. /evidence=ECO:0000250|UniProtKB:O93430	230..235		1/4 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	391..410		5/28 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910