Protein Alignment SecCl and Gabrg3

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_017177467.1
• Gene: Gabrg3 / 14407
• MGIID: 95624
• Length: 468
• Species: Mus musculus
• Alignment Length: 533
• Identity: 128/533 - (24%)
• Similarity: 220/533 - (41%)
• Gaps: 107/533 - (20%)

  Fly    14 LILVLSIWTSVGVKA------EEEECPSMAD---AGSLQQTQLIQRLTHVCR-YDRLERPFEYDS 68
            |:|:|.:::.:..::      |.|:.||...   |...|.|.:...|..:.| ||:..||
Mouse     5 LLLLLCLFSGLHARSRRVEEDENEDSPSNQKWVLAPKSQDTDVTLILNKLLREYDKKLRP----- 64

  Fly    69 DGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAY----KAFNRSDNILGQKHLS 129
            |....|.|:...|||..:..::|..:::::.......:.|.||.:    |....:.|::|
Mouse    65 DIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILTLNSNMVG----- 124

  Fly   130 ERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTV 194
             .:|:|...|.|.:.:........:.|..:..:|.::.:.|:..:..|.:....||.|...|...
Mouse   125 -LIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDAHACPLT 188

  Fly   195 LESWMYNTSDLILEWEPHTPISFDPE-MRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLS 258
            ..|:.|...::|..|..::..:.|.: .||.:::.....:.|.||.:.         ||:|..::
Mouse   189 FSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTS---------AGDYVVMT 244

  Fly   259 FTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPK 323
            ....|.|.:|::.:..|:|.::.|.:||||||::.||:|.|..||.:|:|:..|||:...|:||:
Mouse   245 IYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTTLGITTVLTMTTLSTIARKSLPR 309

  Fly   324 VSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWR-RKENIELKKVNSKYIIKSTLTPRPARRQIGG 387
            |||:...:::...|..|:|.:|:|:|.:|.... ||..|..||.       |.|....:.|.|..
Mouse   310 VSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTIRKKKT-------SQLLHPDSTRWIPD 367

  Fly   388 SLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNY--LTVHPNLPIIRTECAEADTVSICSA 450
            .:|                            .|..:||  |.:.|..|::.|
Mouse   368 RIS----------------------------LQAPSNYSLLDMRPPPPVMIT------------- 391

  Fly   451 RTNN--------DHIVDVDKDKKDTPPTFTTMTPQEIAMW-----------IDRRSRFLFPAMFL 496
             .||        |..|....|.||....|......:...|           :|..||..||..||
Mouse   392 -LNNSMYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRRGRIHIDVSELDSYSRVFFPTSFL 455

  Fly   497 AFNALYWT-FVYV 508
            .||.:||. ::|:
Mouse   456 LFNLVYWVGYLYL 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	119/490 (24%)
		Neur_chan_LBD	44..267	CDD:280998	47/228 (21%)
		Neur_chan_memb	275..503	CDD:280999	68/249 (27%)
Gabrg3	XP_017177467.1	LIC	50..465	CDD:273305	117/483 (24%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	37/195 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810