Protein Alignment SecCl and Gabrg1

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_034382.2
• Gene: Gabrg1 / 14405
• MGIID: 103156
• Length: 465
• Species: Mus musculus
• Alignment Length: 526
• Identity: 119/526 - (22%)
• Similarity: 215/526 - (40%)
• Gaps: 113/526 - (21%)

  Fly    12 ITLILVLSIWTSVGVKAEEEE------------CPSMADAGSLQQTQLIQRLTHVCRYDRLERPF 64
            |.|:|.|.:...|. ||::|:            .|.:.: |.:  ||::..|..  .||...||
Mouse    24 IFLLLTLHLGNCVD-KADDEDDEDLTMNKTWVLAPKIHE-GDI--TQILNSLLQ--GYDNKLRP- 81

  Fly    65 EYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAY----KAFNRSDNILGQ 125
               ..|.| |.|::|.:||..:..::...:::.:..:....:.|.||.:    |....:.|::|
Mouse    82 ---DIGVR-PTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVG- 141

  Fly   126 KHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQF 190
                 ::|:|..||.|.|:|........:.|..:..:|.|:.:.|:..:..|::....||.|:..
Mouse   142 -----KIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAECYLQLHNFPMDEHS 201

  Fly   191 CSTVLESWMYNTSDLILEWEPHTPISFDPE-MRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNY 254
            |.....|:.|..:::..:|:..:....||: .||.::......::|.|..:         .:|:|
Mouse   202 CPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEISHT---------ISGDY 257

  Fly   255 SSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSK 319
            ..::...:|.|.:|::.:..|:|.::.|.:||||||:..||.|.|..||.:|:|:..|||:...|
Mouse   258 IIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARK 322

  Fly   320 NLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQ 384
            :||||||:...:::...|..|:|.:|:|:..::......:.            |:|.
Mouse   323 SLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNNKG------------KTTR-------- 367

  Fly   385 IGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICS 449
             |..|.|::.|.......:.:....|:....|..:.|:               :|.|.
Mouse   368 -GRKLKNKTSASPGLHAGSTLIPMNSISLPQGEDDYGY---------------QCLEG------- 409

  Fly   450 ARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMW-----------IDRRSRFLFPAMFLAFNALYW 503
                           ||....|..........|           ||..||..||..|..||.:||
Mouse   410 ---------------KDCTSFFCCFDDCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYW 459

  Fly   504 T-FVYV 508
            . ::|:
Mouse   460 VGYLYL 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	108/478 (23%)
		Neur_chan_LBD	44..267	CDD:280998	49/227 (22%)
		Neur_chan_memb	275..503	CDD:280999	56/238 (24%)
Gabrg1	NP_034382.2	Neur_chan_LBD	65..270	CDD:280998	49/226 (22%)
		LIC	66..462	CDD:273305	107/475 (23%)
		Neur_chan_memb	277..459	CDD:280999	56/239 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810