Protein Alignment SecCl and Gabrb3

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001033790.1
• Gene: Gabrb3 / 14402
• MGIID: 95621
• Length: 473
• Species: Mus musculus
• Alignment Length: 528
• Identity: 137/528 - (25%)
• Similarity: 239/528 - (45%)
• Gaps: 98/528 - (18%)

  Fly    16 LVLSIWTSVGVKAEEEECPSMADAGSLQ-QTQLIQRLTHVCRYDRLERPFEYDSDGKRLPIVVKT 79
            |:|.||.|..:.....|..|:.|.|::. ..:.:.:|  :..||...||   |..|.  |:.|..
Mouse     8 LLLPIWLSWTLGTRGSEPSSVNDPGNMSFVKETVDKL--LKGYDIRLRP---DFGGP--PVCVGM 65

  Fly    80 RIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSERLWLPHIFFANERE 144
            .|.:..:..::...:.:.:....|..::||||||.....  |:.....::::||:|..:|.|:::
Mouse    66 NIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPL--NLTLDNRVADQLWVPDTYFLNDKK 128

  Fly   145 SSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTSDLILEW 209
            |.:.|...|:.:..|.|:|.|:...|:..:..|.|:.:::|.|:|.|:..:||:.|.|.|:...|
Mouse   129 SFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW 193

  Fly   210 EPHTPISFD-----------PEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFA-GNYSSLSFTVN 262
            .     ..|           |:..:.|:.:..               |:..|| |.|..||.:..
Mouse   194 R-----GGDKAVTGVERIELPQFSIVEHRLVS---------------RNVVFATGAYPRLSLSFR 238

  Fly   263 LKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYI 327
            |||.||:::|..|:||::|..:||||||:..|||..|:.||.:|:|:..|:::...:.|||:.|:
Mouse   239 LKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYV 303

  Fly   328 KVSEVWFLGCTFFIFGSLVEFAFVNTIW-----RRKENIELKKVNSK---------------YII 372
            |..:::.:||..|:|.:|:|:||||.|:     :|::.:..|...:|               .|:
Mouse   304 KAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSEINRVDAHGNIL 368

  Fly   373 KSTLTPRPARRQIGGSLSNESRARSCSSLDN--IVSSTESVRNGNGTVNQGFNNYLTVHPNLPII 435
            .:.:.......::.||:.:  ...|..|.||  |....:|:      ..:|...|:. ..::|..
Mouse   369 LAPMDVHNEMNEVAGSVGD--TRNSAISFDNSGIQYRKQSM------PKEGHGRYMG-DRSIPHK 424

  Fly   436 RTECAEADTVSICSARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNA 500
            :|                  |:.......|...|..|.:..      |||.||.:||..|..||.
Mouse   425 KT------------------HLRRRSSQLKIKIPDLTDVNA------IDRWSRIVFPFTFSLFNL 465

  Fly   501 LYWTFVYV 508
            :||.: ||
Mouse   466 VYWLY-YV 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	126/496 (25%)
		Neur_chan_LBD	44..267	CDD:280998	56/234 (24%)
		Neur_chan_memb	275..503	CDD:280999	65/249 (26%)
Gabrb3	NP_001033790.1	LIC	4..471	CDD:273305	135/525 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3673
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.760