Protein Alignment SecCl and Gabrb1

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_032095.1
• Gene: Gabrb1 / 14400
• MGIID: 95619
• Length: 474
• Species: Mus musculus
• Alignment Length: 495
• Identity: 136/495 - (27%)
• Similarity: 219/495 - (44%)
• Gaps: 112/495 - (22%)

  Fly    57 YDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDN 121
            ||...||   |..|.  |:.|..||.|..:..::...:.:.:....|..::||||:|.....  |
Mouse    48 YDIRLRP---DFGGP--PVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPL--N 105

  Fly   122 ILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPF 186
            :.....::::||:|..:|.|:::|.:.|...|:.:..|.|:|.|:...|:..:..|.|:.:::|.
Mouse   106 LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPL 170

  Fly   187 DQQFCSTVLESWMYNTSDLILEWEPH-------TPISFDPEMRLTEYNM----AQFWHNTTIVQS 240
            |:|.|:..:||:.|.|.|:...|...       ..|.. |:..:.:|.|    .:|   ||
Mouse   171 DEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIEL-PQFSIVDYKMVSKKVEF---TT---- 227

  Fly   241 DGDNLRHGAFAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTS 305
                       |.|..||.:..|||.||:::|..|:||.:|..:||||||:..|||..|:.||.:
Mouse   228 -----------GAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGIT 281

  Fly   306 TMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIW--------------- 355
            |:|:..|:|:...:.|||:.|:|..:::.:||..|:|.:|:|:||||.|:
Mouse   282 TVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQ 346

  Fly   356 --RRKENIELKKVN---SKYIIKSTLTPRPARRQIGGS--LSNESRARSCS-SLDNI-------V 405
              ..|..:|:.||.   ...|:.|||   ..|.:..||  |:..|..::.. |.|:.       :
Mouse   347 SANEKNRLEMNKVQVDAHGNILLSTL---EIRNETSGSEVLTGVSDPKATMYSYDSASIQYRKPL 408

  Fly   406 SSTESVRNGNGTVNQGFNNYLTVH--PNLPIIRTECAEADTVSICSARTNNDHIVDVDKDKKDTP 468
            ||.|           ||...|..|  |....||...::        .:.....:.||:.
Mouse   409 SSRE-----------GFGRGLDRHGVPGKGRIRRRASQ--------LKVKIPDLTDVNS------ 448

  Fly   469 PTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFVYV 508
                          ||:.||..||..|..||.:||.: ||
Mouse   449 --------------IDKWSRMFFPITFSLFNVVYWLY-YV 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	134/490 (27%)
		Neur_chan_LBD	44..267	CDD:280998	57/220 (26%)
		Neur_chan_memb	275..503	CDD:280999	72/259 (28%)
Gabrb1	NP_032095.1	LIC	9..472	CDD:273305	134/492 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810