Protein Alignment SecCl and Gabra6

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_036012221.1
• Gene: Gabra6 / 14399
• MGIID: 95618
• Length: 459
• Species: Mus musculus
• Alignment Length: 388
• Identity: 101/388 - (26%)
• Similarity: 177/388 - (45%)
• Gaps: 41/388 - (10%)

  Fly    11 WITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRLTHVCR-YDRLERPFEYDSDGKRLP 74
            |:.:||.|           |.....:.|.|:.....:.:.|.::.. ||...||    ..|..:
Mouse     7 WLFIILWL-----------ENAQAQLEDEGNFYSENVSRILDNLLEGYDNRLRP----GFGGAV- 55

  Fly    75 IVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLS-ERLWLPHIF 138
            ..|||.|||.....::...:::.|....:..:.|:||.:|.   ...||...:|. .::|.|..|
Mouse    56 TEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFKG---PAEILSLNNLMVSKIWTPDTF 117

  Fly   139 FANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTS 203
            |.|.::|........:.|..|...|.::.:.|:..:..|.|....||.|...|.....|:.|..:
Mouse   118 FRNGKKSIAHNMTTPNKLFRLMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKT 182

  Fly   204 DLILEWEPHTPISFD-PE--MRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKR 265
            ::|..|:.....|.: ||  ..|.:|::.....::..::|:         .|.|..::...:|:|
Mouse   183 EIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSN---------TGEYVIMTVYFHLQR 238

  Fly   266 EIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVS 330
            ::|::::..|.|.:|.|.:|.||||:..::.|.|.:.|.:|:|:..|||.|...:||||||....
Mouse   239 KMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAM 303

  Fly   331 EVWFLG-CTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLSNE 392
            : ||:. |..|:|.:|:|||.||..    .|::.:|...:  .::..||..|:.:...||..|
Mouse   304 D-WFIAVCFAFVFSALIEFAAVNYF----TNLQSQKAERQ--AQTAATPPVAKSKASESLQAE 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	94/356 (26%)
		Neur_chan_LBD	44..267	CDD:280998	50/227 (22%)
		Neur_chan_memb	275..503	CDD:280999	43/119 (36%)
Gabra6	XP_036012221.1	LGIC_ECD_GABAAR_A6	42..239	CDD:349840	48/213 (23%)
		LGIC_TM_GABAAR_alpha	242..337	CDD:349854	37/99 (37%)
		TM1 helix	245..265	CDD:349854	9/19 (47%)
		TM2 helix	274..295	CDD:349854	7/20 (35%)
		TM3 helix	305..327	CDD:349854	11/21 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810