Protein Alignment SecCl and LOC1281130

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_321068.3
• Gene: LOC1281130 / 1281130
• VectorBaseID: AGAMI1_001548
• Length: 212
• Species: Anopheles gambiae
• Alignment Length: 293
• Identity: 76/293 - (25%)
• Similarity: 124/293 - (42%)
• Gaps: 89/293 - (30%)

  Fly   214 PISFDPEMRLTEYNMA-QFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKREIGFYLLDYYLP 277
            |:..:||:.|.:.::: .:..:.||..|          .||::.|:...||:|.:|::|...|:|
Mosquito     4 PLVVNPEIELPQLDISNNYTTDCTIEYS----------TGNFTCLAVVFNLRRRLGYHLFHTYIP 58

  Fly   278 SMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIF 342
            |.:||.:||:|||::.:|.|.|:.||.:::|:..|.::...::||.|||:|..:||...|:.|:|
Mosquito    59 SALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVF 123

  Fly   343 GSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLSNESRARSCSSLDNIVSS 407
            .||:|||.||                     :.:.|...:...|.|..:.|.|
Mosquito   124 LSLMEFAVVN---------------------NYMGPVATKAMKGYSDEDLSEA------------ 155

  Fly   408 TESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICSARTNNDHIVDVDKDKKDTPPTFT 472
                      ::...|.|                           |.||       :....|.:.
Mosquito   156 ----------IDFNKNGY---------------------------NKDH-------RSSEVPRYD 176

  Fly   473 TMT-PQEIAMWIDRRSRFLFPAMFLAFNALYWT 504
            |.. .:|.|:.||:.|||.||..|...|..|||
Mosquito   177 TFCHGRETALCIDKFSRFFFPFSFFILNVTYWT 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	76/293 (26%)
LOC1281130	XP_321068.3	LGIC_ECD	<1..47	CDD:475126	12/52 (23%)
		LGIC_TM_anion	50..>136	CDD:349851	36/106 (34%)
		TM1 helix	50..73	CDD:349851	11/22 (50%)
		TM2 helix	77..101	CDD:349851	6/23 (26%)
		TM3 helix	109..135	CDD:349851	13/46 (28%)