Protein Alignment SecCl and gabra5

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_004911866.1
• Gene: gabra5 / 100494208
• XenbaseID: XB-GENE-980292
• Length: 475
• Species: Xenopus tropicalis
• Alignment Length: 464
• Identity: 123/464 - (26%)
• Similarity: 203/464 - (43%)
• Gaps: 95/464 - (20%)

  Fly    57 YDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKA------ 115
            ||...||    ..|:|: ..|||.|||.....::...:::.:....:..::|:||.::.
 Frog    64 YDNRLRP----GLGERI-TQVKTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLCFQGPMPRLP 123

  Fly   116 FNRSDNILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMN 180
            .|   |:|..|     :|.|..||.|.::|........:.|..|..:|.::.:.|:..|..|.|.
 Frog   124 LN---NLLASK-----IWTPDTFFHNGKKSIAHNITTPNKLLRLEDDGTLLYTMRLTISAECPMQ 180

  Fly   181 FQKFPFDQQFCSTVLESWMYNTSDLILEWEPHTPISF---DPEMRLTEYNMAQFWHNTTIVQSDG 242
            .:.||.|...|.....|:.|..|:|..||...|..|.   :...||.:|::        |.|:.|
 Frog   181 LEDFPMDAHACPLKFGSYAYPNSELRYEWTNITDKSVVVAEDGSRLNQYHL--------IGQTVG 237

  Fly   243 -DNLRHGAFAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTST 306
             :|:  ....|.|:.::...:|||:||::::..|||.:|.|.:|.|||||..::.|.|.:.|.:|
 Frog   238 TENI--STSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTT 300

  Fly   307 MLSFITLSSSQSKNLPKVSYIKVSEVWFLG-CTFFIFGSLVEFAFVNTI------WRRKENIELK 364
            :|:..|||.|...:||||:|....: ||:. |..|:|.:|:|||.||..      |..|:.:|..
 Frog   301 VLTMTTLSISARNSLPKVAYATAMD-WFIAVCYAFVFSALIEFATVNYFTKRSWAWDGKKALEAA 364

  Fly   365 KVNSKYIIKSTLTPRPARRQIGGSLSNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVH 429
            |:..|                                     ..||:  |...:| .::..:...
 Frog   365 KIKKK-------------------------------------EQESL--GRKPIN-SYSGRIPYT 389

  Fly   430 PNLPIIRTECAEADTVSICSARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAM 494
            ||:....|....|:..||        |:...::...::..|:.:::.      ||:.||.:||.|
 Frog   390 PNMSKDLTSSVIANAASI--------HMKTTEEKCAESKKTYNSVSK------IDKMSRIVFPVM 440

  Fly   495 FLAFNALYW 503
            |..||.:||
 Frog   441 FGTFNLVYW 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	123/464 (27%)
		Neur_chan_LBD	44..267	CDD:280998	56/219 (26%)
		Neur_chan_memb	275..503	CDD:280999	63/234 (27%)
gabra5	XP_004911866.1	LIC	25..452	CDD:273305	123/464 (27%)
		LGIC_ECD_GABAAR_A5	62..260	CDD:349839	55/218 (25%)
		Cys-loop	177..191	CDD:349839	5/13 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910