Protein Alignment SecCl and gabra6

DIOPT Version :10

• Sequence 1: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_031754593.1
• Gene: gabra6 / 100488862
• XenbaseID: XB-GENE-6049732
• Length: 455
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 139/509 - (27%)
• Similarity: 221/509 - (43%)
• Gaps: 74/509 - (14%)

  Fly     7 SEIFWITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYDSDGK 71
            |.|.||.:.|.........:.|        |:..|...|:::.||  :..||...||    |.|.
 Frog     3 SFIMWIYIFLCTGKALGNNITA--------ANLHSENITRILDRL--LDGYDNRLRP----SFGG 53

  Fly    72 RLPIV-VKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLS-ERLWL 134
              |:. |||.|||.....::...:::.|....:..:.|:||   .|:....||...:|. .::|.
 Frog    54 --PVTEVKTDIYVTSFGPVSDVDMEYTMDIFFRQTWVDERL---KFDGPTEILRLNNLMVSKIWT 113

  Fly   135 PHIFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWM 199
            |..||.|.::|........:.|..:...|.|:.:.|:.....|.|....||.|...|.....|:.
 Frog   114 PDTFFRNGKKSIAHNMTTPNKLFRIMQNGTVLYTMRLTIKAECPMRLMNFPMDGHACPLKFGSYA 178

  Fly   200 YNTSDLILEWEPHTPISFD-PE--MRLTEYNM-AQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFT 260
            |..|:::..|:.....|.: ||  ..|.:|:: .|...:.|::.:.|:          ||.....
 Frog   179 YPKSEIVYTWKKGPLYSVEVPEESSSLLQYDLVGQKVSSETLLSNTGE----------YSLQVVM 233

  Fly   261 VNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVS 325
            ..|:|:||:|::..|:|..|.|.:|.|.||:..::.|.|.:.|.:|:|:..|||.|...:.||||
 Frog   234 FFLQRKIGYYIIHTYIPCSMTVVLSQVVFWINKESVPARTVAGITTVLTMTTLSISARHSFPKVS 298

  Fly   326 YIKVSEVWFLG-CTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSL 389
            |....: ||:. |..|:|.:|:|||.||..    .|::::|...|...|:.|....||.:
 Frog   299 YATAMD-WFIAVCFAFVFSALIEFAAVNYF----TNLQIQKTMMKAAKKAALAAATARAE----- 353

  Fly   390 SNESRARSCSSLDNIVSSTESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICSARTNN 454
             ||....|.|:. |:.....||.:..   ||.....|.::.:.|.  .|..:..|         .
 Frog   354 -NEFVTLSDSNC-NLKKRINSVASQG---NQSTEGDLPLYEDSPY--NEQTDIPT---------R 402

  Fly   455 DHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWTFVYV 508
            ||::      .||..:..|.|.:     ||:.:|.|||..|..||.:||. ||:
 Frog   403 DHML------SDTTSSQHTGTSK-----IDKYARILFPLSFAGFNLVYWV-VYL 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_648984.2	LIC	43..505	CDD:455710	129/468 (28%)
gabra6	XP_031754593.1	LIC	12..443	CDD:455710	133/497 (27%)
		LGIC_ECD	42..239	CDD:475126	52/215 (24%)