Protein Alignment SecCl and gabrr3

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_017947352.2
• Gene: gabrr3 / 100487991
• XenbaseID: XB-GENE-6039478
• Length: 481
• Species: Xenopus tropicalis
• Alignment Length: 551
• Identity: 137/551 - (24%)
• Similarity: 246/551 - (44%)
• Gaps: 137/551 - (24%)

  Fly    12 ITLILVLSIWTSV-----------------------GVKAEEEECPSMA--------------DA 39
            |.|:|:.|:|...                       .|..|||.....|              |:
 Frog     5 IKLLLLTSLWPGAVLSGFHSLRQKPYSPQHLHHPHQVVNQEEEHSQPAAMRDNRKNASKMRRIDS 69

  Fly    40 GSLQQTQLIQRLTHVCRYDRLERPFEYDSDGKRLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQL 104
            ..::|.: .::|..:..:|...||   ...|..:|:.:.  :.:..:.:::...:.|.|...|:.
 Frog    70 TKVRQMK-SEQLLRIDDHDFAMRP---GFGGSAIPVGID--VQIESIDSISEVDMDFTMTLYLRH 128

  Fly   105 RFQDKRLAYKAF-NRSDNILGQKHLSERLWLPHIFFANERESSILGTDEKDVLTSLSPEGNVIIS 168
            .::|:||::::. |||....|:  |.:::|:|.:||.:.:.|.|..|..::::..:.|:|||:.|
 Frog   129 YWKDERLSFQSTNNRSMTFDGR--LIKKIWVPDVFFVHSKRSFIHDTTMENIMLRVYPDGNVLFS 191

  Fly   169 TRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTSDLILEWE-PHTPISFDPEMRLTEYNMAQFW 232
            .|:..:..|:|:|.:||.|.|.||..|||:.||..||:|.|: .:..:..|..:.|:::.:.:|
 Frog   192 LRITVTAMCFMDFSRFPLDTQNCSLELESYAYNEEDLMLYWKRGNESLKTDEHIALSQFFIEEF- 255

  Fly   233 HNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKREIGFYLLDYYLPSMMIVAISWVSFWLQADASP 297
                   |..:.|...:..|.|:.|.....|:|.|.|:||..|.|:|::|.:||||||:...|.|
 Frog   256 -------SASNGLAFYSSTGWYNRLFINFILRRHIFFFLLQSYFPAMLMVMLSWVSFWIDRRAVP 313

  Fly   298 PRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEVWFLGCTFFIFGSLVEFAFVNTIWRRKENIE 362
            .|:.||.:|:|:..|:.:..|.::|:|||||..:|:......|:|.|::|:|.||.:...:|..:
 Frog   314 ARVSLGITTVLTMSTIITGVSASMPQVSYIKAVDVYLWISFLFVFLSVIEYAAVNYLTTAEERKQ 378

  Fly   363 LKKVNSKYIIKSTLTP--------------RPARRQIGGSL-----SNESRARSCSSLDNI-VSS 407
            ||:..     ||:.|.              ..:...:..|:     |:..||.|.::||.: |..
 Frog   379 LKRRG-----KSSATLNLEAVQAMAFDGCFHDSDADLNFSMHSEESSSRGRAASVATLDAMRVRR 438

  Fly   408 TESVRNGNGTVNQGFNNYLTVHPNLPIIRTECAEADTVSICSARTNNDHIVDVDKDKKDTPPTFT 472
            .:|:|...|.:               |:                 .|:|::|          |:
 Frog   439 KKSIRGNFGRI---------------IL-----------------ENNHVID----------TY- 460

  Fly   473 TMTPQEIAMWIDRRSRFLFPAMFLAFNALYW 503
                          ||.:||.:::.||..||
 Frog   461 --------------SRIIFPTVYIVFNFFYW 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	126/483 (26%)
		Neur_chan_LBD	44..267	CDD:280998	59/224 (26%)
		Neur_chan_memb	275..503	CDD:280999	61/247 (25%)
gabrr3	XP_017947352.2	LIC	77..480	CDD:273305	125/478 (26%)
		LGIC_ECD	98..283	CDD:355788	53/196 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910