Protein Alignment SecCl and gabrb1

DIOPT Version :9

• Sequence 1: NP_001261986.1
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_002664179.2
• Gene: gabrb1 / 100331377
• ZFINID: ZDB-GENE-090313-230
• Length: 484
• Species: Danio rerio
• Alignment Length: 524
• Identity: 130/524 - (24%)
• Similarity: 243/524 - (46%)
• Gaps: 80/524 - (15%)

  Fly     9 IFWITLILVLSIWTSVGVKAEEEECPSMADAGSLQQTQLIQRLTHVCRYDRLERPFEYDSDGKRL 73
            ||.:.:::.|::..|....:..|  ||......:...:|::      .||...||   |..|.
Zfish    16 IFCLLVLVALTLGRSPPAHSVNE--PSNMSYVKVTVDKLLK------GYDIRLRP---DFGGP-- 67

  Fly    74 PIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSERLWLPHIF 138
            |:.|...|.:..:..::...:.:.:....|..::||||:|.....  |:.....::::||:|..:
Zfish    68 PVDVGMSIDISSIDMVSEVNMDYTITMYFQQSWRDKRLSYTGIPL--NLTLDNRVADQLWVPDTY 130

  Fly   139 FANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYNTS 203
            |.|:::|.:.|...|:.:..|.|:|.|:...|:..:..|.|:.:::|.|:|.|:..:||:.|.|.
Zfish   131 FINDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTD 195

  Fly   204 DLILEWEPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFA-GNYSSLSFTVNLKREI 267
            |:...|:..:.::....:.|.::::..:...:..|          .|| |:|..||.:..|||.|
Zfish   196 DIEFYWQGGSSVTGVDNIELPQFSIIDYKTLSKKV----------VFATGSYPRLSLSFKLKRNI 250

  Fly   268 GFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVSEV 332
            |:::|..|:||.:|..:||||||:..|||..|:.||.:|:|:..|:::...:.|||:.|:|..::
Zfish   251 GYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDI 315

  Fly   333 WFLGCTFFIFGSLVEFAFVNTIW-------RRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLS 390
            :.:||..|:|.:|:|:||||.|:       ::|...:..|.|::   ||.|.....:..:.||:
Zfish   316 YLMGCFVFVFLALLEYAFVNYIFFGRGPHLQKKVAEKAAKSNNE---KSRLESNKVQVDVHGSI- 376

  Fly   391 NESRARSCSSLDNIVSSTESVRNGNGTVNQGFN-NYLTVHPNLPIIRTECAEADTVSI------- 447
                  ..::||..:|..|.:.......|..|: :..::....|:...:.....|.||
Zfish   377 ------PLTNLDLRLSGAEMLGALGDPRNTMFSYDSASIQYRKPLTGRDLYGRPTASIERPLAPK 435

  Fly   448 --------CSARTNNDHIVDVDKDKKDTPPTFTTMTPQEIAMWIDRRSRFLFPAMFLAFNALYWT 504
                    ...:.....:.||:.                    ||:.||.:||..:..||.:||.
Zfish   436 KSRLRRRAAQLKVKIPDLTDVNA--------------------IDKWSRVIFPITYTFFNLVYWL 480

  Fly   505 FVYV 508
            : ||
Zfish   481 Y-YV 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecCl	NP_001261986.1	LIC	43..505	CDD:273305	121/485 (25%)
		Neur_chan_LBD	44..267	CDD:280998	53/223 (24%)
		Neur_chan_memb	275..503	CDD:280999	63/250 (25%)
gabrb1	XP_002664179.2	LIC	19..482	CDD:273305	126/518 (24%)
		Neur_chan_LBD	49..250	CDD:280998	53/223 (24%)
		Neur_chan_memb	257..479	CDD:280999	63/251 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810