Protein Alignment CG18265 and die-1

DIOPT Version :9

• Sequence 1: NP_001261984.1
• Gene: CG18265 / 39947
• FlyBaseID: FBgn0036725
• Length: 1322
• Species: Drosophila melanogaster
• Sequence 2: NP_496175.2
• Gene: die-1 / 174569
• WormBaseID: WBGene00000995
• Length: 646
• Species: Caenorhabditis elegans
• Alignment Length: 884
• Identity: 176/884 - (19%)
• Similarity: 268/884 - (30%)
• Gaps: 356/884 - (40%)

  Fly   513 SQSHRGSPNEPSQPTIKQEMSQDAEIKPYQLPEGFREDFTLEQEELSFVPPPRKLPSHLQQQAK- 576
            |.|...|...||..:|..|..:.....|.||.:.     .|...:|        :...||||:.
 Worm    40 SASPTSSSGAPSSSSIMAETDEKDMFMPSQLIQN-----GLANNQL--------MSMILQQQSNQ 91

  Fly   577 -DSNF---------------------NPDKLRRLGVQFPDFFCELCCREYANRYFLRTHKWKRHG 619
             |||.                     |.| |.:...||..
 Worm    92 ADSNIADAGHNNSGAEKNIIELLMSGNAD-LMKFATQFAQ------------------------- 130

  Fly   620 LFVPPEDVAPQPGSKDEAQMASAWPFMPLNLMLAK------------AAAATMDQQEQ------- 665
               ..:.|..:|..:.|:. .|..|.:.||..||.            :||:|....:.
 Worm   131 ---QAKSVDQEPEEQRESS-PSPPPAVSLNSTLASMVFPTTSTATECSAASTTSSVDSAPSTVIV 191

  Fly   666 --EREPEVETD----SEQPSKRIKLEQGQTPPEGYDEDKLNGSVVGLQNLQKLQSMLQQLNDING 724
              ....:..||    ::|||.:.:....:||            :....|.|.:||:|.|:...|
 Worm   192 NGHSNSQSNTDDDDVTQQPSAKKQRTGDETP------------LTPTSNNQLMQSLLAQMGLSN- 243

  Fly   725 KRPLPCHLCGQEQENQYTLRAHLMTEHA----GQMQMPMPIPIPLPDQQAPHPMASLYHGQGNPQ 785
                |.|     |:||..::...|....    |...:|:....||..|
 Worm   244 ----PLH-----QQNQKQMKDESMMFSGLFPQGLAGIPLMFQSPLHQQ----------------- 282

  Fly   786 TPPAPGARSPPGCDLRCQQCDRDFATPQEFKQHIAEVHLGRNGGLSGSPLREGFFTPERPVAPSA 850
                                   ||..|:|:                 || ....||.:
 Worm   283 -----------------------FAGMQDFE-----------------PL-SALSTPNK------ 300

  Fly   851 GGPGTPVAPAANRPPYTLTPTSSYCEICNKELCNKYFMKTHMQRMHGIEI-ENGAQIGGV----- 909
             |.|.....::|        ..::|:|||||:|||||::|||.:||||.| ||...|..:
 Worm   301 -GSGVKRQYSSN--------NKNFCDICNKEVCNKYFLRTHMLKMHGIVIDENKTVIANIDTSIK 356

  Fly   910 --------VCNICNKELCSKYFLRVHKHNTHGIIEEGSPLPQPRGQNGVKADAAAAVAASQPSQA 966
                    .|:.|.....::..||.|:.:.||::    ||..||               :.|:::
 Worm   357 EREGELTFRCDTCRTMFKTRNQLRQHRQDVHGVL----PLSTPR---------------NNPNKS 402

  Fly   967 QQDQDLNVSPPTV-----EGSGGSSSNSAHEVCPLCSRQFRSFKWLRSHLMNEHGTAGVERLREM 1026
                    |.||.     ..||.:|::.:.|.|.||.::. |...:..|:..:|
 Worm   403 --------SVPTTPNGANNNSGPNSASMSEEKCALCDKRV-SPSMMMLHMAQDH----------- 447

  Fly  1027 DTTQSSTRSKPNSPTLKIPNGSGSNPGAAGAGAGNTAPNLAQALQNLNAQHIFGQMQQQQIPKMP 1091
                                        .||.|.|...|...|        |.||..|....||
 Worm   448 ----------------------------FGAAAANGDLNQMMA--------ILGQRNQSTEEKM- 475

  Fly  1092 PLPLPGMFGEQSARFKEYQCSLCPFSTPYYAFLFIHERSHALLNNGGEGLELPMETPPPQPSRSS 1156
                       |:...|  |:.|.:.|.....|.:|...|..:                    |.
 Worm   476 -----------SSNLLE--CTDCSYKTRDPKNLDLHMERHIKM--------------------SE 507

  Fly  1157 GKSRSKSSKSMVAPPPAKSEETEPPLEPTNLSTSAPKVASRSPSTGAGSPPASSPKAT---SSTS 1218
            .|.|.             .|:.:..|:.|  :.:|.::..::.:...|...|::...|   ..|.
 Worm   508 AKGRG-------------DEDEDVALQLT--TEAALQMVVQNQNQYDGDSTAAALNLTFKNDGTK 557

  Fly  1219 PKIQRRRSTSKPPTTPNGLGSATGGHRSAATSPFEGCGELANGIGKPASYAQPDGAEEAYQMQAF 1283
            .:|:..::|.         ......|.|.:.||   .|.:..|.||       :..|:|:..|:|
 Worm   558 KEIEEEKATG---------NHERNSHTSGSISP---SGSIPEGFGK-------NIGEKAFPTQSF 603

  Fly  1284 HLQPADQDSEMQFAPALVYLPVRVRASESATLSFRLTPA 1322
            .::..|...|. ....|..||||........|.|.|.||
 Worm   604 LIKCNDDSGEF-LTEFLAQLPVRSVIDGPRQLVFNLHPA 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18265	NP_001261984.1	PHA03377	<1169..>1316	CDD:177614	29/149 (19%)
die-1	NP_496175.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161027
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S12616
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0016829
OrthoInspector	1	1.000	-	-		oto18802
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR21190
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.980