DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12229 and AT3G55810

DIOPT Version :9

Sequence 1:	NP_648980.1	Gene:	CG12229 / 39945	FlyBaseID:	FBgn0036723	Length:	571	Species:	Drosophila melanogaster
Sequence 2:	NP_191140.1	Gene:	AT3G55810 / 824747	AraportID:	AT3G55810	Length:	492	Species:	Arabidopsis thaliana

Alignment Length:	543	Identity:	114/543 - (20%)
Similarity:	200/543 - (36%)	Gaps:	132/543 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 ARRRKRKRYYHLG-------LVAKLVTETTHDELRRMLENGTYTFHVDTVGNKPDELKAILDTMN 121
            |.|.|.|....||       ::.||:...|.|.||..:.|
plant    13 ALRSKTKIVCTLGPVSRSVEMIEKLLKAETLDNLRTAMNN------------------------- 52

  Fly   122 IAISAHSAERELRLTTGL----ALEINGECCRVGRLRNNCTVMLARGGVVTLTTDESYRYKGFKE 182
                           ||:    .|:..|...|.|.|:....:.|.:|..:|::.|  |:.:|...
plant    53 ---------------TGILCAVMLDTKGPEIRTGFLKEGKPIQLNQGQEITISID--YKIEGDSN 100

  Fly   183 IVYVINLRCYLASVQLGDIVMIGREVRGKVVKTLREALTVMIIDA--GLV----------ASYDF 235
            |: .::.:.....|:.||:::..   .|.:      :|||:..|.  |||          .....
plant   101 II-SMSYKKLAEDVKPGDVILCS---DGTI------SLTVLSCDKSFGLVRCRCENSTILGERKN 155

  Fly   236 IELPRQCHALDPDLYPDLYMKD----LEMAASLNANYVVLPKIRCKSFLRAVRQTLNS-DFNLKL 295
            :.||    .:..|| |.|..||    ::.......:.:.|..:|..|.|..||:.|.. ..|:.|
plant   156 VNLP----GIVVDL-PTLTEKDKEDIIQWGVPNKIDIIALSFVRKGSDLTEVRKLLGEHSKNIML 215

  Fly   296 I-------GMIDFEYVRSNMLDLLGIIK--LVDYIWIPDMFNVNCCVYNYIMEDVLPISQCQKKP 351
            :       |:::.|.:..|. |...:.:  |...|.|..||        ...:.::.::....||
plant   216 MSKVENQEGVMNCEKILENS-DAFMVARGDLGMEIQIEKMF--------LAQKTMIKMANALGKP 271

  Fly   352 VI-GTVPLERCSDF---KRFELHD----FLWKVDAIHIQKSPWCNKYP--------LIVKKLMPI 400
            |: .|..||..:..   .|.|..|    .|...|.:.:........:|        .|.|:....
plant   272 VVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPEAAVLTMSRICKEAEDF 336

  Fly   401 KDYRVGAVQNKMVLKSILTSYQTIVNFIIRTISSIECQAIFLFTTCETASVALSRIEIYCPVY-V 464
            .||.:...:...:|...|:..:::...::.|..|:...||.:.|.....:..:::.....|:. |
plant   337 IDYDILHKKTLGMLSLPLSPIESLAASVVSTAQSVFASAIVVLTKGGYTAELVAKYRPSVPILSV 401

  Fly   465 MVP-LEETDDAETITCK---VELARALHLRRNMHPVLYT----KDLN-ECSYSPIEFGVDFMRKK 520
            :|| :.:.:|.| ::|.   ..:||...:.|.:.||:.|    :|.| :.:...|...:.|.:.|
plant   402 IVPEIAQGNDIE-MSCSDSVAHVARRGLIYRGIIPVVATGSSARDSNKDATEEMINLAIGFAKTK 465

  Fly   521 GCLEVGDFVVTLEVGKEDKDNVV 543
            |..:.||.:|.|.  |.|..:||
plant   466 GICKNGDSIVALH--KIDGSSVV 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12229	NP_648980.1	pyruv_kin	103..530	CDD:273424	95/482 (20%)
CG12229	NP_648980.1	Pyruvate_Kinase	126..530	CDD:304951	95/459 (21%)
AT3G55810	NP_191140.1	PLN02461	1..492	CDD:215255	114/543 (21%)
AT3G55810	NP_191140.1	Pyruvate_Kinase	17..491	CDD:304951	112/539 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870