DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12229 and AT3G52990

DIOPT Version :9

Sequence 1:	NP_648980.1	Gene:	CG12229 / 39945	FlyBaseID:	FBgn0036723	Length:	571	Species:	Drosophila melanogaster
Sequence 2:	NP_566976.1	Gene:	AT3G52990 / 824465	AraportID:	AT3G52990	Length:	527	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	102/521 - (19%)
Similarity:	188/521 - (36%)	Gaps:	136/521 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 GTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRL-TTGLALEINGECCRVGRLRNNCTVM 160
            |...:|.:|           ||.:.:|:.:......:.| |.|..|::..        ::...:.
plant    64 GDADYHQET-----------LDNLKVAVRSTKKLCAVMLDTVGPELQVIN--------KSEKAIT 109

  Fly   161 LARGGVVTLTTDESYRYKGFKEIVYVINLRCYLASVQLGDIVMIGR----------------EVR 209
            |...|:||||.::.  .:...|:: .||......:|:.||.:.:|:                ||:
plant   110 LKADGLVTLTPNQD--QEASSEVL-PINFNGLAKAVKKGDTIFVGQYLFTGSETTSVWLEVDEVK 171

  Fly   210 G-KVVKTLREALTVMIIDAGLVASYDFIELPRQCHALDPDLYPDLYMKDLEMAAS---------L 264
            | .|:...|.|.|:    ||.:    |.....|.|.   || |.|..||.|:.::         |
plant   172 GDDVICLSRNAATL----AGSL----FTLHSSQVHI---DL-PTLTEKDKEVISTWGVQNKIDFL 224

  Fly   265 NANYVVLPKIRCKSFLRAVRQTLNSDFNLKLIGMIDFEYVRSNMLDLLGIIKLVDYIWIPD---- 325
            :.:|       |: ....||||...   ||.:|.:....:.:.:.::.|:....:.:...|
plant   225 SLSY-------CR-HAEDVRQTREM---LKKLGDLSQTQIFAKIENVEGLTHFDEILQEADGIIL 278

  Fly   326 ---MFNVNCCVYNYIMEDVLPISQCQK--KPVIGTVPLERCSDF---KRFELHDFLWKV----DA 378
               ...::.......:.....:.:|..  ||.:.|..::..:|.   .|.|..|....|    ||
plant   279 SRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVLTRVVDSMTDNLRPTRAEATDVANAVLDGSDA 343

  Fly   379 IHIQKSPWCNKYPLIVKKLMPIKDYRVGAVQNKMVLKSI------------LTSYQTIVNFIIRT 431
            |.:........||  |:.:..:.  |:.|...|:..:.:            :|..::|.:..:|.
plant   344 ILLGAETLRGLYP--VETISTVG--RICAEAEKVFNQDLYFKKTVKYVGEPMTHLESIASSAVRA 404

  Fly   432 ISSIECQAIFLFTTCETASVALSRIEIYCPVY-VMVPLEETDDAETITCKVELARALHLRRNM-- 493
            ...::...|..||:...|:..:::.....||. |::|..:|:.     .|...:.|...|:::
plant   405 AIKVKASVIICFTSSGRAARLIAKYRPTMPVISVVIPRVKTNQ-----LKWSFSGAFEARQSLIV 464

  Fly   494 -----------HPVLYTKDLNECSYSPIEFGVDFMRKKG----------CLEVGDFVVTLEVGKE 537
                       ||...|...||   |.::..:|..:..|          |.:|||..|...:..|
plant   465 RGLFPMLADPRHPAESTSATNE---SVLKVALDHGKHAGVIKSHDRVVVCQKVGDASVVKIIELE 526

  Fly   538 D 538
            |
plant   527 D 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12229	NP_648980.1	pyruv_kin	103..530	CDD:273424	97/505 (19%)
CG12229	NP_648980.1	Pyruvate_Kinase	126..530	CDD:304951	93/482 (19%)
AT3G52990	NP_566976.1	PLN02765	1..527	CDD:215409	100/519 (19%)
AT3G52990	NP_566976.1	Pyruvate_Kinase	30..523	CDD:304951	100/515 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870